Research Labs

Physician-scientist Prasad S. Adusumilli studies tumor immunology and the development of T-cell‒mediated immunotherapy for thoracic malignancies and pleural-based diseases.

Chemical biologist Daniel Bachovchin designs selective inhibitors to study enzymes and pathways in cancer and immune system signaling.

Physician-scientist Samuel Bakhoum studies the role of chromosomal instability in tumor evolution and metastasis.

Surgeon scientist Vinod Balachandran develops novel immunotherapies for pancreatic cancer.

The Brown Lab studies how the tissue environment shapes immune cell fate and function during early life immune development, inflammation, and cancer.

Physician-scientist Nai-Kong Cheung focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children.

Jonathan Coleman is a physician-scientist focused on translational research, cancer genomics, and patient-derived organoid models in the study of urologic malignancies. Ongoing work includes the development of local ablative therapies, their influence on the tumor microenvironment, and implications for therapy response.

Physician-scientist Liang Deng studies poxvirus interface with the immune system and the development of poxviruses as oncolytic and immunotherapy for cancers.

The Diehl lab studies how the microbiota and other exogenous factors regulate development and function of the intestinal immune system.

The Greenbaum lab utilizes techniques from statistical physics, information theory, and evolutionary biology to better understand the role of self/non-self discrimination in tumor evolution, model response to immunotherapies, and quantify drivers of virus and cancer evolution.