The Anna-Katerina Hadjantonakis Lab: Projects

The Mammalian Blastocyst: Development & Stem cells

The in vivo establishment of a bona fide pluripotent cell population, and in vitro derivation, maintenance and differentiation of lineage-specific stem cells.

Gastrulation: A Paradigm for Tissue Morphogenesis

Loss of pluripotency, and the coordination of cell fate specification, epithelial-to-mesencymal transition (EMT) and cell movement drive the formation of the three germ layers; ectoderm, mesoderm & endoderm.

The Generation of Tools and Development of Methods for Live Imaging Mouse Embryos & Stem Cells

The visualization of live cell behaviors operating in situ combined with the power of mouse genetics towards understanding the mechanisms regulating development, homeostasis and disease progression.