Our laboratory investigates innate and adaptive immune responses to infection by microbes, with a particular focus on the role of the intestinal microbiota and the mucosal immune system in preventing infections by antibiotic-resistant bacterial pathogens. We study the role of specific commensal bacterial species in providing resistance against Vancomycin-resistant Enterococcus, highly antibiotic-resistant Klebsiella pneumoniae and Clostridium difficile.
Eric G. Pamer, MD
Director, Lucille Castori Center for Microbes, Inflammation, and Cancer
Research FocusPhysician-scientist Eric Pamer studies T cell and innate inflammatory responses to bacterial and fungal infections.
EducationMD, Case Western Reserve University School of Medicine
- Lewis BB, Carter RA, Ling L, Leiner I, Taur Y, Kamboj M, Dubberke ER, Xavier J, Pamer EG. Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence. MBio. 2017; 8(4). pii: e00885-17.
- Becattini S, Littmann ER, Carter RA, Kim SG, Morjaria SM, Ling L, Gyaltshen Y, Fontana E, Taur Y, Leiner IM, Pamer EG. Commensal microbes provide first line defense against Listeria monocytogenes infection. Journal of Experimental Medicine. 2017;214(7):1973-1989.
- Member, Association of American Physicians (2011)
- Fellow, Infectious Diseases Society of America (2010)
- Member, American Society for Clinical Investigation (1998)
- Pew Scholar in the Biomedical Sciences, Pew Charitable Trust (1994)