Chemical Biology Program

The Heeseon An Lab

Research

Heeseon An
Heeseon An, PhD

Human cells orchestrate up to ~20,687 proteins to maintain cell growth and survival. Upon environmental change, cells dynamically remodel their proteomic landscape by two simultaneous processes: enhancing the synthesis of proteins that respond to the altered cellular conditions and degrading a subset of the pre-existing proteome. Any defect in this nature’s fine-tuned system hampers regulated cell growth as exemplified by cancer and neurodegenerative disorders. To fully understand the underlying pathology of the dysregulated proteostasis system, Heeseon An’s lab studies the regulatory mechanisms of protein translation (ribosome) and degradation processes (the ubiquitin proteasome system and autophagy) in health and disease. Importantly, we develop chemical, biological, and proteomics tools to enable quantitative analyses of the cell biological events.

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Heeseon An

Heeseon An, PhD

  • Heeseon An’s lab develops chemical, biological, and proteomics tools to study protein homeostasis of sub-cellular organelles.
  • BS and MS, Chemistry, Seoul National University
  • PhD, Chemistry, Northwestern University
  • Postdoc, Cell Biology, Harvard Medical School
AnH@mskcc.org
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Mel-Quann Hodge
Mel-Quann Hodge

Lab/ Administrative Assistant

Liang Sun
Liang Sun

Research Fellow

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Heeseon An discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


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This page and data include information for a specific MSK annual disclosure period (January 1, 2020 through disclosure submission in spring 2021). This data reflects interests that may or may not still exist. This data is updated annually.

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