The Heeseon An Lab

Heeseon An: Publications


An, H.*; Ordureau, A.*; Koerner, M.; Paulo, J.A.; Harper, J.W. (2020) Systematic Quantitative Analysis of Ribosome Inventory During Nutrient Stress. Nature, 583, 303-309. * equal contribution

Ordureau, A., Paulo, J.A., Zhang, J., An, H., Swatek, K.N., Cannon, J.R., Wan, Q., Komander, D., Harper J.W. (2020) Global landscape and dynamics of Parkin and USP30-dependent ubiquitylomes in iNeurons during mitophagic signaling. Molecular Cell, 77, 1124-1142

An, H.; Harper, J.W. (2020) Ribosome Abundance Control Via the Ubiquitin-Proteasome System and Autophagy. J. Mol. Biol. 432, 170-184, review article

An, H.; Ordureau, A.; Paulo, J.A.; Shoemaker, C.J.; Denic, V.; Harper, J.W. (2019) TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress, Molecular Cell, 74, 891-908.

  • This work is featured in two commentaries; (1) “Picky Eating at the ER-phagy Buffet.” Trends Biochem Sci. 2019 Sep;44(9):731-733, (2) “TEX264 is a major receptor for mammalian reticulophagy”, Autophagy. 2019 Oct;15(10):1677-1681

An, H.; Harper, J.W. (2018) Systematic Analysis of Ribophagy in Human Cells Reveals Bystander Flux During Selective Autophagy, Nat. Cell Biol., 20, 135-143.

  • This work is featured in a News & Views article in Nat. Cell. Biol. 2018, 20, 122-124

Juenemann, K.; Jansen, A.H.P.; van Riel, L.; Merkx, R.; Mulder, M.P.C.; An, H.; Statsyuk, A.; Kirstein, J.; Ovaa, H.; Reits, E.A. (2018) Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies. Sci. Rep., 8, 1405.

Misra, M.; Kuhn, M.; Lobel, M.; An, H.; Statsyuk, A.V.; Sotriffer, C.; Schindelin, H. (2017) Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme, Structure, 25, 1120-1129.

An, H.; Statsyuk, A.V. (2016) Facile Synthesis of Covalent Probes to Capture Enzymatic Intermediates during E1 Enzyme Catalysis, Chem. Comm., 52, 2477-2480.

An, H.; Statsyuk, A.V. (2015) An Inhibitor of Ubiquitin Conjugation and Aggresome Formation. Chem. Sci. 6, 5235-5245.

An, H.; Krist, D.; Statsyuk, A.V. (2014) Crosstalk between Kinases and Nedd4 family Ubiquitin Ligases. Mol. BioSyst., 10, 1643-1657, review article

An, H.; Statsyuk, A.V. (2013) Development of Activity-Based Probes for Ubiquitin and Ubiquitin-Like Protein Signaling Pathways. J. Am. Chem. Soc., 135 (45), 16948-16962.

Koh, M.; Park, J.; An, H.; Park, S.B. (2011) Ratiometric analysis of zidovudine (ZDV) incorporation by reverse transcriptases or polymerases via bio-orthogonal click chemistry. Chem. Comm., 47, 7614-7616.

An, H.; Eum, S-J.; Koh, M.; Lee, S.K.; Park, S.B. (2008) Diversity-oriented Synthesis of Privileged Benzopyranyl Heterocycles from S-cis Enones. J. Org. Chem., 73, 1752-1761.