The Kim lab is interested in the role that epigenetic regulation plays in pluripotency and cancer. Specifically, we are using comparative methylome studies to assess genome-wide patterns of methylation in cells derived from various tissue types and donors, including pluripotent stem cells generated via multiple methodologies. The goal of these studies is to identify the mechanisms that regulate DNA methylation and to define their contribution to the cell’s ability to self-renew, differentiate, and function normally.
Kitai Kim, PhD
Research FocusStem cell biologist Kitai Kim studies epigenetic regulation of DNA methylation in stem cells and cancer.
EducationPhD, University of Wisconsin
- Biological significance of suppression of oxidative phosphorylation in pluripotent stem cell reprogramming. Zhang C, Skamagki M, Ananthanarayanan A, Zhao R, Li H, Kim K*. Cell Reports. 2017 Nov; 21(8):2058-2065.
- Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells. Liu Z, Ross CA, Khodadadi-Jamayran A, Skamagki M, Rocha ELD, Zhang W, Kong D, Chang CW, Feng J, Townes TM, Li H, Kim K*, and Zhao R. Kim K and Zhao R share co-senior-authorship. Stem Cell Reports. 2017 Nov 14;9:1-14.