
Immunology Program
The Marcel van den Brink Lab
Research

Immuno-oncology is increasingly becoming an important therapy for a variety of cancers. As Head of the Division of Hematologic Malignancies and an Attending Physician of the Adult Bone Marrow Transplantation Service, I see patients undergoing a bone marrow transplantation. In my lab, I study novel strategies to improve immune therapies for cancer patients with a special emphasis on the role of the intestinal microbiome in (patho)physiology and therapy, Chimeric Antigen Receptor T cell therapy, and regeneration of thymic function to improve T cell immunity.
Please visit our official website at vandenbrinklab.org!
Research Projects
MSK Offers Students a Spectrum of Education Unlike Any Other

van den Brink Lab group photo
Featured News


Publications
Smith M, Dai A, Ghilardi G, Amelsberg KV, Devlin SM, Pajarillo R, Slingerland JB, Beghi S, Herrera PS, Giardina P, Clurman A, Dwomoh E, Armijo G, Gomes ALC, Littmann ER, Schluter J, Fontana E, Taur Y, Park JH, Palomba ML, Halton E, Ruiz J, Jain T, Pennisi M, Afuye AO, Perales MA, Freyer CW, Garfall A, Gier S, Nasta S, Landsburg D, Gerson J, Svoboda J, Cross J, Chong EA, Giralt S, Gill SI, Riviere I, Porter DL, Schuster SJ, Sadelain M, Frey N, Brentjens RJ, June CH, Pamer EG, Peled JU, Facciabene A, van den Brink MRM, Ruella M. Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nat Med. 2022 Mar 14. doi: 10.1038/s41591-022-01702-9. Epub ahead of print. PMID: 35288695.
Miltiadous O, Waters NR, Andrlova H, Dai A, Nguyen CL, Burgos da Silva M, Lindner S, Slingerland J, Giardina P, Clurman A, Armijo GK, Gomes AL, Lakkaraja M, Maslak PG, Scordo M, Shouval R, Staffas A, O’Reilly RJ, Taur Y, Prockop S, Boelens JJ, Giralt S, Perales MA, Devlin SM, Peled JU, Markey KA, van den Brink MRM. Early intestinal microbial features are associated with CD4 T cell recovery after allogeneic hematopoietic transplant. Blood. 2022 Jan 21:blood.2021014255. doi: 10.1182/blood.2021014255. Epub ahead of print. PMID: 35061893.
People

Marcel R. M. van den Brink, MD, PhD
- Physician-scientist Marcel R. M. van den Brink studies the immunology of bone marrow transplantation with a particular focus on intestinal microbiome and strategies to enhance thymus and immune reconstitution.
- MD, PhD, Universiteit Leiden
- [email protected]
- Email Address
- 646-888-2304
- Office Phone
- View physician profile
- Physician profile
Members

- 212-639-2814
- Office Phone

- 212-639-8727
- Lab Phone

- National and Kapodistrian University of Athens, Greece
- 646-888-2317
- Lab Phone



- Christian Medical College (MD), Vellore, India


- 1. Bachelor of Science in Biological Sciences. Lehigh University. 2021.

- Ph.D. in Biology, Microbiology
- University of Lisbon, Portugal, 2014
- M.Sc. in Biology
- University of Evora, Portugal, 2005
- B.Sc. in Biology
- University of Evora, Portugal, 2003


- University of Connecticut, CT | Weill Cornell Graduate School of Medical Sciences, NY
- 646-888-2317
- Lab Phone



- Bachelors in Biological Sciences with a concentration in Pathobiology- Drexel University, Philadelphia, 2017-2021

- 646-888-2317
- Office Phone


- Colgate University | NY
- Gerstner Sloan Kettering Graduate School | NY
- 646-888-2317
- Lab Phone

- MPH Candidate, New York University

- MPA, Columbia University
- Rutgers University

- MD: Technion, Israel Institute of Technology | Haifa, Israel
- PhD: Bar Ilan University | Ramat Gan, Israel





- Bachelor of Arts (Biology) – 2011
- Master of Science (Community Health) – 2013
- Master of Biomedical Science – 2015




Clinical Research Dietitian

Research Assistant, Molecular Microbiology Facility

Senior Research Scientist

Research Fellow

Hematology Oncology Fellow

Senior Research Scientist

Research Associate

Computational Biologist II

Instructor

Research Fellow

Senior Research Technician

Manager, Molecular Microbiology Facility

Computational Biologist

Research Technician

Scientific Research Lead

Clinical Research Specialist

Graduate Student

Assistant Attending Lv. 1

Administrative Assistant, Sr

Research Associate

Research Scholar

Senior Research Scientist

Visiting Investigator

CAR T Cell Research Technician

Research Technician

Pediatric Hematology/Oncology Clinical Instructor

Clinical Research Coordinator

Graduate Student

Graduate Student

Hematologic Oncologist

Research Scholar

Program Coordinator

Senior Project Manager

Hematology Oncology Fellow
Research Fellow

Data Engineer

Project Coordinator

Assistant Attending, L1

Research Project Manager

Clinical Research Coordinator

Senior Administrative Assistant

Graduate Research Assistant

Computational Biologist

Research Assistant, Molecular Microbiology Facility

Visiting Investigator

Senior Research Technician

Clinical Research Coordinator


Lab Manager

- Binghamton University

- CUNY Hunter College
- Pace University, Lienhard School of Nursing


- Binghamton University

- Monash University, Melbourne, Australia
- 646-888-2317
- Lab Phone


- Weill Cornell Graduate School of Medical Sciences
- 646-888-2317
- Lab Phone

- Technische Universität München - Medical School, Ludwig-Maximilians-Universität München - Medical School Undergraduate
- 646-888-2317
- Lab Phone


- BA from New York University
- MD from Robert Wood Johnson Medical School
- 646-888-2317
- Lab Phone
- Mysore Medical College (MD), Karnataka, India and Medizinische Hochschule Hannover (PhD), Hannover, Germany
- 646-888-2317
- Lab Phone



- Barnard College of Columbia University 2015
- 646-888-2317
- Lab Phone

- Oregon Health and Science University School of Medicine, Portland, Oregon
- 646-888-2317
- Lab Phone

- Albert Einstein College of Medicine | Bronx, New York


- University of Nantes, France University Pierre et Marie Curie, France

- 646-888-2317
- Lab Phone

- MPA Candidate, Villanova University
- Rutgers University

- University of Puerto Rico BS
- Vanderbilt University School of Medicine MD, PhD
- Memorial Sloan Kettering Cancer Center Radiation Oncology Residency
- 646-888-2317
- Lab Phone

- Universidade Federal do Rio de Janeiro, UFRJ, Rio De Janeiro, Brazil

- Boston University, BA
- University of Michigan Ann Arbor
- 646-888-2317
- Lab Phone
- Ludwigs-Maximilians-University, Munich, Germany
- Harvard Medical School, Boston, MA
- University of Cape Town, Capetown, SA.
- 646-888-2317
- Office Phone
- Pace University
- Morgan State University

- Hokkaido University Graduate School of Medicine, Sapporo, Japan
- Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

- (646) 888-2304
- Office Phone
- (646) 888-2317
- Lab Phone

- New York University
- 646-888-2304
- Office Phone
- 646-422-4052
- Office Fax

- University of Gothenburg, Sweden
- (646) 888-2304
- Office Phone
- (646) 888-2317
- Lab Phone

- 646-888-2317
- Office Phone
- 646-888-2317
- Lab Phone
- Chemical Engineering (PhD), NYU Polytechnic School of Engineering

- University of Perugia, Perugia, Italy
- 646-888-2317
- Lab Phone

- Monash University, Melbourne, Australia
- 646-888-2317
- Lab Phone
Lab Alumni

Administrative Secretary
Postdoctoral Research Fellow

Research Technician

SKI Administrative Assistant, Senior

Clinical Research Coordinator

Graduate Research Assistant

Clinical Research Dietitian

SKI Administrative Assistant, Sr.

Research Project Associate

Administrative Assistant
Graduate Student

Senior Research Scientist

Research Technician

Postdoctoral Fellow
Administrative Secretary

Graduate Research Assistant

Research Technician

Research Technician
Postdoctoral Research Fellow
Research Technician
Research Fellow
Research Technician, Molecular Microbiology Facility

Research Project Associate
Postdoctoral Research Fellow

Computational Biologist, Sr.
Postdoctoral Research Fellow
Research Technician

Research Technician
Postdoctoral Research Fellow

Research Project Associate
Research Fellow

Research Fellow

Research Scholar

Research Technician

Assistant Attending, Bone Marrow Transplant

Assistant Attending
SKI Administrative Assistant II

Administrative Assistant
Research Technician
Postdoctoral Research Fellow
Research Technician
Postdoctoral Research Fellow
Research Technician

Research Technician

Research Technician, Sr.

Research Technician

Research Technician

Research Technician

Postdoctoral Research Fellow
Graduate Student
Research Technician

Research Fellow

Assistant Attending Lv. 1

Medical Student, University Hospital Eppendorf, Hamburg, Germany
Administrative Secretary

Administrative Secretary
Research Technician
Research Fellow

Research Technician

Project Coordinator
Research Fellow

Radiation Oncology Resident, Research Fellow
Postdoctoral Research Fellow

Visiting Research Fellow

Senior Research Technician to Dr. Lia Palomba

Research Technician
Feodor Lynen Scholar for Experienced Researchers (Alexander von Humboldt-Foundation)
Postdoctoral Research Fellow
Assistant to Marcel van den Brink, MD, PhD
Administrative Secretary
Assistant to Marcel van den Brink, MD, PhD
Research Technician
Postdoctoral Research Fellow
Postdoctoral Research Fellow

Visiting Investigator

Research Technician

Research Technician, Sr.

Senior Research Assistant

Senior Project Coordinator

Research Fellow

Visiting Investigator
Research Technician

Research Fellow

Visiting Investigator
Research Associate

Graduate Student
Postdoctoral Research Fellow

Visiting Investigator
Postdoctoral Research Fellow

Graduate Research Assistant

Research Technician
Research Technician, Graduate Student

Howard Hughes Medical Institute Medical Research Fellow

Senior Research Technician

Research Trainee
Achievements
- Head of the Division of Hematologic Malignancies at MSKCC (2008 - present)
- Royal Dutch Academy of Sciences (2020)
- International Society for Experimental Hematology: Till and McCulloch Lectureship Award (2015)
- Alan N. Houghton Chair in Immunology at MSKCC (2007)
- Howard Hughes Physician Scientist Award (1996)
Lab News & Events

Lab social at Treadwell Park!

Some of our lab members attending the US Open
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Lab Manager
The Van den Brink Lab studies clinically relevant complications in hematopoietic cell transplantation (HCT) and aims to develop novel therapeutic strategies to improve patient outcomes. We are looking for a Lab Manager to join our team! This will include supervising and performing technical and administrative tasks. This candidate will directly manage research technicians and indirectly oversee other laboratory staff, oversee equipment needs and manage inventory, and manage lab safety programs to ensure compliance with all applicable regulations. Pay Range $76,900 to $123,000
Research Assistant
As a Research Assistant you will assist in performing research activities in collaboration with internal/external personnel to complete science based projects. You will independently craft, plan, and develop new methods and technologies for project advancement. You will maintain a high level of expertise through familiarity with scientific literature and implement a quality assurance plan, as well as participate in scientific conferences and contribute to scientific journals. Department: Research - Laboratory Location: New York, NY Salary: $63,700-$98,700 yrly.
Get in Touch
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Lab Head Email
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Office Phone
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Office Fax
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Lab Phone
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Lab Fax
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Marcel R. M. van den Brink discloses the following relationships and financial interests:
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Ceramedix
Provision of Services -
DKMS
Fiduciary Role/Position; Provision of Services -
Da Volterra
Provision of Services -
Garuda Therapeutics
Provision of Services -
GlaxoSmithKline
Provision of Services -
Juno Therapeutics
Intellectual Property Rights -
LyGenesis, Inc.
Provision of Services
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MJH Life Sciences
Provision of Services -
Pluto Immunotherapeutics
Ownership / Equity Interests; Provision of Services -
Rheos Medicines, Inc
Provision of Services -
Seres Therapeutics
Intellectual Property Rights; Ownership / Equity Interests; Provision of Services -
Smart Immune SAS
Provision of Services (uncompensated) -
ThymoFox, Inc.
Ownership / Equity Interests -
WindMIL Therapeutics, Inc.
Provision of Services
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].