The Marcel van den Brink Lab: Featured News

Share
Share
How gut reactions are shaping cancer treatment
An explosion of interest in the workings of the gut microbiome is fueling career and funding opportunities in a wide array of fields. MSK's Marcel van ...
Headshots of MSK hematologic oncologist Jae Park and physician-scientist Marcel van den Brink
How Do Gut Microbes Affect the Success of CAR T Immunotherapy? New Answers From MSK
In an effort to improve patients’ response to immunotherapy, MSK researchers have studied how microorganisms in the gut affect outcomes in people receiving CAR T therapy.
MSK and SKI's Highly Cited Researchers.
Memorial Sloan Kettering Cancer Center Tops Prestigious List of Highly Cited Researchers
Memorial Sloan Kettering Cancer Center (MSK) is proud to announce that it is ranked among the top 20 organizations with the greatest number of highly cited scientific researchers worldwide, according to the annual list of Highly Cited Researchers published by the Institute for Scientific Information at Clarivate.
Five MSK researcher headshots
ASCO 2021 Research Roundup: Focus on Immunotherapy
Read about the latest findings in immunotherapy from the 2021 annual meeting of the American Society of Clinical Oncology (ASCO).
Medical oncologists Niloufer Khan and Jonathan Peled
Success of Bone Marrow Transplants Using Patients’ Own Cells Impacted by Gut Bacteria
The first large study of its kind has found that having a healthy microbiota before starting the process of a bone marrow transplant using a patient’s own cells (autologous) leads to fewer complications after the procedure.
Finding
Systems biologist Joao Xavier in his lab
MSK Study Is the First to Link Microbiota to Dynamics of the Human Immune System
MSK researchers have shown for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.
Finding
Illustration of Enterococcus
Study in Mice Suggests Lactose in the Diet Feeds Dangerous Gut Bacteria When the Immune System Is Compromised
Lab mice who had lactose removed from their diets had a decreased risk of infection with the Enterococcus bacterium.
In the Lab
Microscopy image of vancomycin-resistant Enterococcus
Researchers Identify a Bacterial Species That Could Protect against Hospital-Acquired Infections
MSK researchers are reporting that a bacterial species called Blautia producta appears to release a substance that kills harmful bacteria.
Roundup
ASH meeting signage
Advances in Myeloma, Lymphoma, and Bone Marrow Transplant Announced at the 2018 ASH Meeting
Learn more about the work of MSK researchers being presented at the 2018 meeting of the American Society of Hematology.
Finding
Jonathan Peled speaks during a press conference
Gut Microbes May Protect People Having Bone Marrow Transplants
For the first time, researchers have found an association between the makeup of the microorganisms in the body before a bone marrow transplant and a patient’s survival afterward.
Outreach
High school students in an MSK laboratory
Growing Cells and Future Scientists: MSK Hosts High School Students for Day of Exploration
Students from Manhattan’s Urban Academy Laboratory School paid a visit to Marcel van den Brink’s lab at MSK.
In Brief
side-by-side bone marrow slides showing different levels of immune cell growth
Gut Microbes Help Feed a Regrowing Immune System after Bone Marrow Transplant
A study conducted in mice suggests the value of healthy gut flora in people receiving a bone marrow transplant.
In the Lab
Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy
New Hope for Repairing a Damaged or Aging Immune System
Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.
In the Lab
Cross sections of mouse femurs showing bone marrow after radiation and no drug (left) and after radiation plus drug (right).
Prostate Cancer Drug Could Protect Bone Marrow from Damage Caused by Radiation
Researchers are working on a novel method for addressing a common complication of cancer treatment — bone marrow suppression.
In the Lab
Pictured: Marcel van den Brink & Robert Jenq
Bacteria May Hold the Key to Preventing Dangerous Side Effect of Transplants
Research suggests that the presence of a type of bacteria called Blautia, which occurs naturally in the body, may prevent graft-versus-host disease, a potentially fatal side effect of bone marrow and stem cell transplants.