Molecular Biology Program

The Mark Ptashne Lab

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Research

pictured: Mark Ptashne
Mark S. Ptashne, PhD
Virginia and Daniel K. Ludwig Chair

We study basic mechanisms of gene regulation, primarily in yeast at the moment, but with an eye to understanding many basic aspects of biological regulation.

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Publications

Narayan, S., Bryant., G.O., Shah, S., Berrozpe, G., Ptashne, M. (2017) OCT4 and SOX2 Work as Transcriptional Activators in Reprogramming Human Fibroblasts. Cell Reports. 20 (7):1585-1596. PubMed

Berrozpe, G., Bryant, G.O., Warpinski, K., Spagna, D., Narayan, S., Shah, S., Ptashne, M. (2017) Polycomb Responds to Low Levels of Transcription. Cell Reports. 20(4):785-793.

Wang, X., Ptashne, M. (2015) Nucleosome avidities and transcriptional silencing in yeast. Current Biology 25 , 1215-1220.

Ptashne, M. (2014) Reflections: The Chemistry of Gene Regulation. Journal of Biological Chemistry 289, 5417-5435.

Berrozpe, G., Bryant, G.O., Warpinski, K.A., Ptashne, M. (2013) Regulation of a Mammalian Gene Bearing a CpG Island Promoter and a Distal Enhancer” Cell Reports 4, 445-453.

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People

pictured: Mark Ptashne

Mark S. Ptashne, PhD

Virginia and Daniel K. Ludwig Chair

  • Molecular biologist Mark Ptashne studies mechanisms of gene regulation.
  • PhD, Harvard University
[email protected]
Email Address
212-639-2297
Office Phone
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PDF File

Members

Georgina Berrozpe

Senior Research Scientist

Gene Bryant, PhD
Gene Bryant

Senior Research Scientist

James Doon

Laboratory Member

Santosh Narayan, Ph.D.
Santosh Narayan

Senior Research Scientist

Mark Ptashne, PhD
Mark Ptashne

Member, Ludwig Chair of Molecular Biology

Xin Wang, PhD
Xin Wang

Senior Research Scientist

Lab Affiliations

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Mark S. Ptashne discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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