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Leila Sellam

Graduate Research Assistant

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Taha Merghoub, PhD

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Increased glucose uptake due to high energy requirements is one of the major hallmarks of tumor metabolism. Accelerated tumor glycolysis generates an unfavorable immune microenvironment that limits intra-tumor T-cell infiltration and activation. My work focuses on targeting tumor glycolysis to potentiate anti-tumor T-cell responses and the activity of immunotherapy.