Project description:

My research focuses on the interaction of the gut microbiome, graft versus leukemia effect (GVL) effect and immune reconstitution after allo-HSCT. The VDB group has previously shown that the diversity of the gut microbiome correlates with immune function and leukemia relapse after allo-HSCT. Based on these findings, I am investigating how gut microbiome can modulate immune reconstitution and regulate GVL. I hope that these studies could lead to microbial interventions which help reduce relapse risk of hematological malignancies post HSCT.

Grants/Awards/Highlights:

2015, 2018, 2021 National Natural Science Foundation of China (81400146,81873445, 82070182) as PI

2020 EBMT Young Ambassadors

2019 Beijing Nova Program(Z191100001119120) 2019 as PI

2019 Best Young Abstract Awards of European Society for Blood and Marrow Transplantation (EBMT)

2019 National Key R&D plan of China (2017YFA0104500, 2021YFA1100902) 2017,2021 as Co-PI

 

Education:

PhD in Hematology. Peking University, Beijing, China. 2013

MD of 7-Year Clinical Program. Tongji Medical College of HUST, Wuhan, China, 2010

 

Employment:

2013-present: Resident→Hematology Fellow→Attending Doctor→Associate Professor of Peking University People’s Hospital, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation; Beijing, China.  2013-

2022-present: Visiting Scholar of VDB Lab

 

Publications:

https://orcid.org/0000-0001-6625-9523

 

VDB project:

https://www.mskcc.org/research/ski/labs/marcel-van-den-brink/microbiota…