Recent News: Chemical Biology

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14 News Items found

In The Lab

Computational “Hive Mind” Helps Scientists Solve an Enzyme’s Cryptic Movements

The breakthrough gives an unprecedented look at the varied and shifting poses of a protein in action.

Two clusters of colored blobs with a diagram in the middle

Science Byte

Scientists Discover Keys to Immune Response against Anthrax

Researchers clarify how the immune system activates an inflammatory defense against pathogens.

Ribbon diagram of an anthrax protein.

Feature

Remembering Jerard Hurwitz, a Giant of Molecular Biology

MSK colleagues pay tribute to molecular biologist Jerard Hurwitz’s scientific accomplishments and passion for discovery.

Memorial Sloan Kettering molecular biologist Jerard Hurwitz

In the Clinic

Experimental Cancer Drug Developed at MSK Leads to New Approach for Treating Alzheimer's Disease

A family of drugs developed at MSK targets disrupted processes in cells in diseases related to aging.

Chemical biologist Gabriela Chiosis in a laboratory

Q & A

Building a Safer Opioid: MSK Research Seeks to Develop New Ways to Relieve Pain

Science could lead to a new type of opioid drug that blocks pain but has a lower potential for addiction or abuse.

MP1104 binding to the kappa opioid receptor

In the Lab

Researchers Gain Insight into How a Drug Fires Up an Immune Response to Cancer

Scientists have learned that a drug activates a form of highly inflammatory programmed cell death called pyroptosis — a discovery that sheds light on immune function.

Image of fireball-type explosion on black background.

In the Lab

Communal Behavior within Cells Makes Cancers Easier to Target

Findings about proteins called molecular chaperones are shedding new light on possible approaches to cancer treatment.

Bees in a hive

In the Lab

New Drug Developed at MSK Starves Acute Myeloid Leukemia of a Signaling Fix

An innovative collaboration between basic scientists and clinical researchers has led to a promising new drug for AML.

Light micrograph of white blood cells from a patient with acute myeloid leukemia.

In the Lab

Miniature Device Could Unlock the Promise of Some Kidney Cancer Drugs

Memorial Sloan Kettering scientists have engineered a tiny particle that could ferry drugs directly to the kidneys and prevent their uptake in other organs.

Proximal tubule of the kidney.

Finding

Hsp90: A Very Promising Target for Cancer Therapy

A small molecule discovered at MSK called PU-H71 blocks the growth of cancer cells and enables doctors to image tumors.

Pictured: Gabriela Chiosis