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16 News Items found

In the Lab

Research Clarifies How IDH Mutations Cause Cancer

The MSK team’s goal was to get at the underlying defects in cells that these mutations cause.

DNA winding around histones

In th Lab

Cellular “Garbage Collectors” Are Key to Cancer’s Growth

A new study suggests a way to target cancer by interfering with its system of waste removal.

A cartoon depicting a cleaning crew

Feature

What Is Epigenetics, and Why Is Everyone Talking about It?

Epigenetics is frequently in the news, but there's lots of confusion about just what it entails.

A calico cat

In Brief

Scientists Identify How Gene Mutation Drives a Deadly Childhood Cancer

Synovial sarcoma is an aggressive cancer primarily affecting children and young adults. A new study gets to the bottom of it.

Illustration of girl standing in front of charging bull

Feature

The Man behind the Prize: How Paul Marks Shaped Modern Cancer Research

Recent advances in epigenetic and targeted therapies owe a lot to the foresight of former MSK President Paul Marks, who believed in the importance of basic research.

Former MSK president Paul Marks

In the Lab

When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma

The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.

A scientist looks at illustrations of chromosomes.

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.

In the Lab

Scientists Home in on Treatment Advance for Chemotherapy-Resistant Small Cell Lung Cancer

An epigenetic mechanism may make small cell lung cancer vulnerable to a new kind of attack.

MSK scientists Charles Rudin and John Poirier

Q&A

No Sugar, No Cancer? A Look at the Evidence

A lot has been written about the relationship between sugar and cancer. Most of it is wrong.

photo of sugary foods like candy, donuts, and cupcakes

Feature

After Years of Neglect, Cancer Biologists Return to a Forgotten Field: Metabolism

Scientists are dusting off their biochemistry textbooks in the hunt for clues to cancer.

a circuit board