Recent News: Genome Integrity

15 News Items found
Michel Talagrand, Maria Jasin, Carrie Lam Cheng Yuet-ngor, and Edward Stone
Meet Maria Jasin, an Award-Winning Biologist Who Studies DNA Repair
Maria Jasin, a member of the Sloan Kettering Institute’s Developmental Biology Program, discusses her research.
In the Lab
An illustration of proteins serving as bar-code-reading drones
“Molecular Origami” Enables Proteins to Serve as Specialized Delivery Vehicles, Study Finds
Scientists at the Sloan Kettering Institute have identified a fundamentally new type of protein-sorting system in cells.
an illustration of a cigarette burning and smoke entering lungs
How Do Cigarettes Cause Cancer?
Everyone knows that cigarettes cause cancer. But what do we know about how they do it?
In the Lab
Illustration of cells with blue nuclei that have green DNA bits floating in the cytoplasm
Escape Artists: Cancer Cells Mimic Immune Cell Activity to Spread
Researchers have discovered that cancer cells may hijack an immune response to spread from a primary tumor to distant organs.
Science Byte
Graphic of shattered, red, DNA double-helix
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers
A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.
Science Byte
Blue cells containing small red dots on a green and black background
Lifeguard on Duty: Looking at DNA Repair under a Microscope
Learn about what DNA repair looks like under a microscope.
In the Lab
Cartoon illustration of DNA double-helix segment (with arms and legs) “jumping” to from one part of the double-helix to another.
Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers
Researchers have discovered a genetic mechanism that may trigger most childhood cancers.
Molecular biologist John Petrini of the Sloan Kettering Institute.
Understanding the DNA-Damage “First Responders”: John Petrini at Work
Scientists know that cancer can result from mistakes in DNA repair. But understanding what controls the repair process itself has been a hard nut to crack.
Science Byte
Illustration of DNA with green wrench making adjustments to a nut on the double helix.
A Clean Break: Scientists Make Surprising Discoveries about DNA Repair
A study reveals unexpected insights into how cells prepare broken DNA strands to be rejoined, preventing mutations that can cause cancer.
Christina Leslie and John Petrini
Expanding the Impact of Precision Medicine to Fuel Discoveries
MSK’s Functional Genomics Initiative will enable basic scientists to take full advantage of the massive amount of data produced by tumor sequencing.