Recent News: Genome Integrity

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15 News Items found

Q & A

Meet Maria Jasin, an Award-Winning Biologist Who Studies DNA Repair

Maria Jasin, a member of the Sloan Kettering Institute’s Developmental Biology Program, discusses her research.

Michel Talagrand, Maria Jasin, Carrie Lam Cheng Yuet-ngor, and Edward Stone

In the Lab

“Molecular Origami” Enables Proteins to Serve as Specialized Delivery Vehicles, Study Finds

Scientists at the Sloan Kettering Institute have identified a fundamentally new type of protein-sorting system in cells.

An illustration of proteins serving as bar-code-reading drones

Feature

How Do Cigarettes Cause Cancer?

Everyone knows that cigarettes cause cancer. But what do we know about how they do it?

an illustration of a cigarette burning and smoke entering lungs

In the Lab

Escape Artists: Cancer Cells Mimic Immune Cell Activity to Spread

Researchers have discovered that cancer cells may hijack an immune response to spread from a primary tumor to distant organs.

Illustration of cells with blue nuclei that have green DNA bits floating in the cytoplasm

Science Byte

Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.

Graphic of shattered, red, DNA double-helix

Science Byte

Lifeguard on Duty: Looking at DNA Repair under a Microscope

Learn about what DNA repair looks like under a microscope.

Blue cells containing small red dots on a green and black background

in the Lab

Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.

Cartoon illustration of DNA double-helix segment (with arms and legs) “jumping” to from one part of the double-helix to another.

Feature

Understanding the DNA-Damage “First Responders”: John Petrini at Work

Scientists know that cancer can result from mistakes in DNA repair. But understanding what controls the repair process itself has been a hard nut to crack.

Molecular biologist John Petrini of the Sloan Kettering Institute.

Science Byte

A Clean Break: Scientists Make Surprising Discoveries about DNA Repair

A study reveals unexpected insights into how cells prepare broken DNA strands to be rejoined, preventing mutations that can cause cancer.

Illustration of DNA with green wrench making adjustments to a nut on the double helix.

Announcement

Expanding the Impact of Precision Medicine to Fuel Discoveries

MSK’s Functional Genomics Initiative will enable basic scientists to take full advantage of the massive amount of data produced by tumor sequencing.

Christina Leslie and John Petrini