Recent News: Hematologic Malignancies

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19 News Items found

In The Lab

Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal

Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.

An illustration of a samurai and a crab.

In the Lab

Something New Under the Sun: Study in Leukemia Finds Role for Helios Protein

MSK researchers have found that a protein that contributes to one type of leukemia when it’s missing can lead to the formation of a different leukemia type when it’s present.

An illustration shows Helios, the ancient Greek sun god, unwinding DNA

In Brief

Gut Microbes Help Feed a Regrowing Immune System after Bone Marrow Transplant

A study conducted in mice suggests the value of healthy gut flora in people receiving a bone marrow transplant.

side-by-side bone marrow slides showing different levels of immune cell growth

In the Lab

Step by Step: Stem Cell Approach Provides New Models for Studying How Acute Myeloid Leukemia Progresses

A new laboratory tool will allow researchers to study the progression from normal cells to myelodysplastic syndromes to an aggressive type of leukemia.

Histology images of stem cells and AML cells

In the Lab

Study Suggests Ways to Make Bone Marrow Transplants Safer for People with Blood Cancers

A dangerous treatment side effect called graft-versus-host disease may be lessened with genetically engineered immune cells.

Physician-scientists Marcel van den Brink and Michel Sadelain

In the Clinic

New Research Shows AML Is Not One Disease, But 11 or More

Learn how researchers plan to use new genetic information about acute myeloid leukemia to tailor treatments.

Microscopic view of blood cells from bone marrow in a case of acute myeloid leukemia

Q&A

Setting Cancer Cells on the Right Path: A New Leukemia Drug Shows Growing Promise

An experimental drug for acute myelogenous leukemia might potentially help many more patients than previously thought by controlling epigenetic processes, according to a recent MSK study.

Epigenetics

Decoder

What Is Epigenetics?

Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.

DNA wrapped around histones

In the Lab

Compound from Tropical Plant Targets Key Cancer-Causing Genes

Memorial Sloan Kettering researchers have found a naturally occurring compound that can destroy cancer cells in mice by targeting MYC, a cancer-causing gene that has remained elusive until now.

An origami crane illustrates the importance of RNA folding for regulating gene translation. The bolded sequences on the crane’s wings indicate the portion that is critical for the manufacture of many cancer-causing proteins.