Recent News: Solid Tumor Oncogenesis

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25 News Items found

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Science Byte

Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.

Graphic of shattered, red, DNA double-helix

in the Lab

Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.

Cartoon illustration of DNA double-helix segment (with arms and legs) “jumping” to from one part of the double-helix to another.

In the Lab

Manipulating a Single Gene Turns Colorectal Cancer Cells Back to Normal

For the first time, scientists have shown that the gene APC, which is mutated in the vast majority of colorectal cancers, might be a promising target for future therapies.

Organoid cell structures fluorescing in blue, green, and purple.

In the Lab

Outsmarting Cancer’s Survival Skills

A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.

MSK investigators Joan Massagué and Anna Obenauf

Announcement

Expanding the Impact of Precision Medicine to Fuel Discoveries

MSK’s Functional Genomics Initiative will enable basic scientists to take full advantage of the massive amount of data produced by tumor sequencing.

Christina Leslie and John Petrini

In the Lab

Disorderly DNA: Researchers Simulate a Common Cause of Lung Cancer

MSK scientists have created a mouse model that replicates a subtype of non-small cell lung cancer caused by a chromosomal rearrangement.

Cancer biologist Andrea Ventura

In the Lab

Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.

Pictured: Scott Lowe

In the Lab

Researchers Find Clues to How Breast Cancer Can Infiltrate the Brain

A new study sheds light on what enables breast cancer cells to spread to the brain and presents a potential target for drugs.

Pictured: Johanna Joyce