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10 News Items found
Researchers Russell Kunes, Thomas Walle, and Dana Pe'er
MSK Researchers Develop New Open-Source Method To Improve Decoding of Single-Cell Data

MSK researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data — and made it freely available to researchers around the world.
In the Lab
In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).
Scientists Rewrite the Textbook of Organ Development, One Cell at a Time

A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.
Roundup
Sign for AACR scientific meeting featuring collage of images
Highlights from MSK at the 2018 American Association for Cancer Research Meeting

Read up on the latest developments in several key areas of cancer research, including genomic mapping, disease modeling through CRISPR, CAR T therapy, and cancer stem cells.
In the Lab
abstract red and blue lines suggestive of metabolic pathways
Scientists Create First-of-Its-Kind Metabolic Road Map of Cancer

The online resource will serve as a benchmark for researchers studying metabolism and cancer.
Mount Rushmore viewed through face-detection software.
Making a Splash: Researchers Apply Face-Detection Technology to the Study of Genes

Taking a cue from smartphone technology, scientists are using face-recognition algorithms to improve RNA interference.
In the Lab
Researchers at MSK have devised a technique, based on machine learning, that can predict the DNA binding preferences of a protein called a transcription factor.
A Netflix-Inspired Approach to Understanding Biology and Medicine

Computers currently help us choose our favorite movies, books, and TV shows. Will personalized medicines be next?
In the Lab
Pictured: William Lee, Chris Sander & Nils Weinhold
Beyond the Usual Suspects: Study of Noncoding DNA Reveals New Mutations Linked to Cancer

In a study of patient tumor samples, researchers have found common mutations in parts of the genome that control gene regulation.
Decoder
Pictured: Gum ball machines
What Is Tumor Heterogeneity?

Understanding tumor heterogeneity may be the next big quest in cancer science, as differences between cells within a tumor can have important consequences for how cancers are diagnosed and treated.
In the Lab
Pictured: Cancer cell lines
Do Cancer Cell Lines Really Resemble Tumors? Now Researchers Can Tell

A recent study found that the cell lines most commonly used for research on ovarian cancer are not the most suitable.
In the Lab
Pictured: Douglas Levine and Petar Jelinic
New Web Tool Helps Researchers Explore How the Genome Changes in Cancer

Memorial Sloan Kettering investigators hope their new web tool will improve the accessibility of large-scale genome-sequencing information for cancer researchers everywhere, and accelerate research and therapeutic discovery.