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Learn more 193 News Items found Finding Knowledge of Inherited Gene Mutations Increasingly Can Guide Cancer Treatment Wednesday, June 16, 2021 An analysis of patients who received molecular testing at MSK has found that about half of those with hereditary gene mutations could benefit from treatment with therapies that target those alterations. Taking the STING Out of Cancer: Discovery about How Cancer Cells Evade Immune Defenses Inspires New Treatment Approach Monday, December 28, 2020 The research identifies a protein called ENPP1 as a potential drug target in the treatment of advanced cancers with chromosome instability. Year in Review: Top 10 MSK Cancer Science Breakthroughs of 2020 Monday, December 21, 2020 Take a look back at some of the biggest cancer science stories from this past year. Going the Distance: How DNA Enhancers Communicate with Their Target Genes Monday, September 21, 2020 Scientists at the Sloan Kettering Institute are learning how far-flung regions of genes connect to start the process of making proteins. Finding A Never-Before-Seen Cell State May Explain Cancer’s Ability to Resist Drugs Thursday, July 23, 2020 Identified in mice, this unusual cell state emerges early during tumor evolution and gives tumors enormous malleability. The ABCs of BCG: Oldest Approved Immunotherapy Gets New Explanation Friday, July 17, 2020 BCG has been used to treat bladder cancer for more than 30 years. Scientists are still learning how it works. In the Lab Just Add Sugar: How a Protein’s Small Change Leads to Big Trouble for Cells Tuesday, June 30, 2020 A study from investigators in the Sloan Kettering Institute uncovers the details of how a key protein called GRP94 becomes disrupted, leading to cancer and other diseases. In the Lab How Fruit Flies Know When They've Mated Thursday, June 25, 2020 Research from investigators at the Sloan Kettering Institute shows how a brain circuit controls mating behavior in fruit flies. In the Lab A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target Monday, June 22, 2020 New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma. In the Lab A New Target for CAR T Cells: Senescence-Related Diseases Wednesday, June 17, 2020 From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs. In the Lab Breaking Up Is Hard to Do (Especially for Sex Chromosomes) Wednesday, May 27, 2020 One’s big, one’s small. Somehow, they make it work. In Brief Cancer Stem Cells’ Reliance on a Key Amino Acid Could Be an Exploitable Weakness Tuesday, May 26, 2020 The discovery links metabolism to the way cancer stem cells form tumors. In the Lab How Small Chromosomes Compete with Big Ones for a Cell’s Attention Wednesday, May 6, 2020 During meiosis, small chromosomes risk being lost in the shuffle. Here’s how they hold their own. In the Lab New Discovery Explains How the Prostate Gland Regenerates Itself Thursday, April 30, 2020 Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found. In the Lab Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells Monday, April 27, 2020 MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover new findings about acute myeloid leukemia. In the Lab Research Uncovers Details about How Gut Microbes Influence the Immune System Wednesday, April 22, 2020 Investigators have shown how gut microbes promote the formation of a type of immune cell called regulatory T cells. In the Lab Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer Tuesday, March 31, 2020 Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors. In the Lab Researchers Discover Stem Cells That May Drive Aggressive Behavior in Glioblastoma Thursday, February 20, 2020 Researchers have discovered uncanny similarities between cells found in brain tumors and a type of stem cell that’s important for building the brain during fetal development. In the Lab Shape-Shifting Stem Cells Are Key to Cancer Metastasis and Immune Evasion Monday, February 10, 2020 By assuming primitive regenerative identities, cancer cells gain the adaptability they need to establish tumors in new parts of the body. Finding Study Reveals a New Way That Stress and Aging Lead to Alzheimer’s Thursday, January 16, 2020 A targeted approach being developed to treat certain cancers may also be effective for Alzheimer’s disease. 1 2 3 4 5 6 7 8 9