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30 News Items found
In the Lab
Different viewpoints of the STING pathway
Putting the STING in Immunotherapy: Research Focuses on Ways to Improve Cancer Treatments

Researchers are looking for ways to make cancer cells more visible to the immune system.
Finding
Scanning electron micrograph (SEM) of T lymphocyte cells (blue) attached to a red cancer cell.
Discovery of Unusual Cell Type Could Help Guide Immunotherapy

A newly identified group of immunosuppressive cells could provide insight into the effects of immunotherapy drugs.
Roundup
Sign for AACR scientific meeting featuring collage of images
Highlights from MSK at the 2018 American Association for Cancer Research Meeting

Read up on the latest developments in several key areas of cancer research, including genomic mapping, disease modeling through CRISPR, CAR T therapy, and cancer stem cells.
In the Clinic
Jedd Wolchok and Charlotte Ariyan in the lab
Chemotherapy-Immunotherapy Combination Aims to Knock Out Melanoma with a One-Two Punch

A new approach for treating melanoma combines the immunotherapy drug ipilimumab with chemotherapy that treats only the area affected by cancer.
In the Clinic
Medical oncologist Jae Park
Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

The study represents 20 years of research at MSK.
In the Lab
Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy
New Hope for Repairing a Damaged or Aging Immune System

Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.
In the Lab
Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.
Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.
Feature
T cells on the loose.
T Is for T Cell: The Science Behind Immunotherapy

By deciphering the biology of T cells, MSK scientists gave immunotherapy a boost.
Q&A
Illustration of immune cell opening as if on hinge and boxing glove coming out.
New Approach Could Boost Immunotherapy for Breast Cancer

A protein on certain immune cells is a promising target for making immunotherapy more effective against breast cancer.
In the Lab
A chess match
Resistance Is Futile: Targeted Treatment Makes Stubborn Cancers Responsive to Immunotherapy

New research on an experimental drug provides hope for better responses to immunotherapy.