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35 News Items found

In the Lab

Neutrophil Recruitment — What's Damage Got to Do with It?

Immune cells called neutrophils are the first responders to sites of infection. A new study probes what gets them there.

Wounding a zebrafish tail fin triggers a wave of calcium that signals damage and recruits neutrophils

In Brief

Gut Microbes Help Feed a Regrowing Immune System after Bone Marrow Transplant

A study conducted in mice suggests the value of healthy gut flora in people receiving a bone marrow transplant.

side-by-side bone marrow slides showing different levels of immune cell growth

In the Lab

New Hope for Repairing a Damaged or Aging Immune System

Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.

Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy

In the Lab

Prostate Cancer Drug Could Protect Bone Marrow from Damage Caused by Radiation

Researchers are working on a novel method for addressing a common complication of cancer treatment — bone marrow suppression.

Cross sections of mouse femurs showing bone marrow after radiation and no drug (left) and after radiation plus drug (right).

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Finding

Is Neurodegenerative Disease a Kind of Cancer?

New findings from experiments done in mice suggest a surprising cause of common neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

A network of neurons

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.

In the Lab

CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level

What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.

CAR T cells attacking cancer

Feature

T Is for T Cell: The Science Behind Immunotherapy

By deciphering the biology of T cells, MSK scientists gave immunotherapy a boost.

T cells on the loose.