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329 News Items found

In The Lab

Scientists Home In On “Equation” for Muscle Cell Size

By Matthew Tontonoz

A new study in flies reveals a previously unknown type of cooperation at work in muscle cells.

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Mutlinucleated muscle cells from flies

Feature

Beyond Sugar: What Cancer Cells Need to Grow

By Matthew Tontonoz

While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.

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a cartoon of a cancer cell spooning glutamine from a jar

Science Byte

Scientists Discover Keys to Immune Response against Anthrax

By Jim Stallard

Researchers clarify how the immune system activates an inflammatory defense against pathogens.

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Ribbon diagram of an anthrax protein.

In the Lab

Scientists Rewrite the Textbook of Organ Development, One Cell at a Time

By Matthew Tontonoz

A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.

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In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).

Feature

An Old Protein Gets a New Look: Researchers Target TGF-ß to Make Immunotherapy More Effective

By Julie Grisham

Drugs that block the action of TGF-ß may make checkpoint inhibitors more effective.

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Model of TGF-beta molecule

In the News

AACR 2019 Research Roundup: Nanosensors for Cancer, New Immunotherapy Targets, a Road Map of Metastasis, and CAR T Fratricide

By Matthew Tontonoz Jim Stallard

Read our key takeaways from the second half of the American Association for Cancer Research’s 2019 annual meeting.

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an illustration of cancer metastasis

In the Clinic

CAR Therapy for Solid Tumors Draws Attention at Annual Cancer Conference

By Matthew Tontonoz

Results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.

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Scientific Image

In the Lab

A Death Wish That Allows Worms to Thrive — and What It Tells Us About Cancer Biology

By Julie Grisham

Researchers discover that a curious type of cell death plays a role in normal development.

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Microscopic image of cancer cells and C. elegans cells undergoing entosis.

In th Lab

Cellular “Garbage Collectors” Are Key to Cancer’s Growth

By Matthew Tontonoz

A new study suggests a way to target cancer by interfering with its system of waste removal.

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A cartoon depicting a cleaning crew

MSK Heroes

From Controversy to Consensus: How Charlotte Friend Changed Cancer Biology

By Matthew Tontonoz

In honor of Women's History Month, meet the scientific hero who shook up cancer research with her unusual findings.

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Microbiologist Charlotte Friend