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In the Lab
Fluorescent image of mouse prostate gland
New Discovery Explains How the Prostate Gland Regenerates Itself

By Matthew Tontonoz

Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.
Tags: Discoveries & Advances · Lab Research · Solid Tumor Oncogenesis

Two Sloan Kettering Institute Scientists Elected to Esteemed National Academy of Sciences

Membership is a widely accepted mark of excellence in science and considered one of the highest honors a scientist can receive.

  • Tuesday, April 28, 2020
In the Lab
An illustration of a samurai riding a horse along a strand of RNA. The samurai’s sword is changing the letter A to the letter I.
Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells

By Julie Grisham

MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover new findings about acute myeloid leukemia.
Tags: Sloan Kettering Institute · Discoveries & Advances · Lab Research · Hematologic Malignancies · Targeted Therapy
In the Lab
Bacteroides bacteria under the microscope
Research Uncovers Details about How Gut Microbes Influence the Immune System

By Julie Grisham

Investigators have shown how gut microbes promote the formation of a type of immune cell called regulatory T cells.
Tags: Sloan Kettering Institute · Cancer Immunotherapy & Vaccines · Discoveries & Advances · Lab Research · Immunology · Microbiome & Inflammation
In the Lab
A drawing of a pancreatic tumor represented as a barren landscape, blood vessels as rivers, and immune cells as ships with ammunition.
Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer

By Matthew Tontonoz

Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors.
Tags: Immunotherapy · Targeted Therapy · Discoveries & Advances
In the Lab
Medical image showing vasculature of colon tumor in mice.
Imaging Technique Combines Light and Sound to Monitor Drug Response

By Jim Stallard

A new imaging approach involving lasers and sound waves produces high-resolution pictures of tumor blood vessels.
Tags: Imaging · Tumor Microenvironment
In the Lab
black and white image of cells under a microscope
Researchers Discover Stem Cells That May Drive Aggressive Behavior in Glioblastoma

By Julie Grisham

Researchers have discovered uncanny similarities between cells found in brain tumors and a type of stem cell that’s important for building the brain during fetal development.
Tags: Sloan Kettering Institute · Discoveries & Advances · Lab Research · Neuroscience & Neuro-Oncology · Stem Cell Biology
In the Lab
An illustration of lung develop alongside tumor evolution
Shape-Shifting Stem Cells Are Key to Cancer Metastasis and Immune Evasion

By Matthew Tontonoz

By assuming primitive regenerative identities, cancer cells gain the adaptability they need to establish tumors in new parts of the body.
Tags: Developmental Biology · Discoveries & Advances · Lab Research · Metastasis & Drug Resistance · Stem Cell Biology
Finding
An illustration of a magnifying glass over a brain.
Study Reveals a New Way That Stress and Aging Lead to Alzheimer’s

By Julie Grisham

A targeted approach being developed to treat certain cancers may also be effective for Alzheimer’s disease.
Tags: Research · Sloan Kettering Institute · Chemical Biology · Discoveries & Advances
Feature
Cancer biologist Scott Lowe at a white board
Researchers Find that Vitamin B6 Contributes to Survival of Acute Myeloid Leukemia Cells

By Julie Grisham

This research marks the first time researchers have found a connection between vitamin B6 and cancer.
Tags: Sloan Kettering Institute · Cancer Metabolism · Discoveries & Advances · Lab Research · Hematologic Malignancies