The Chiosis lab uses a unique chemical biology approach to understand, diagnose, and treat cellular processes associated with chronic molecular stress, with the ultimate goal of developing novel therapeutic options for use in the clinic.

Computational chemist John Chodera uses statistical mechanics, molecular modeling, and automated biophysical experiments to help identify new potential therapeutics and investigate mechanisms of drug resistance in cancer.

Yael David’s lab develops and applies methods in chemical biology toward studying epigenetic regulation and its correlation with disease states.

The Kushal Dey lab focuses on developing machine learning models and computational pipelines that integrate genomic and epigenomic data.

The Diehl lab studies how the microbiota and other exogenous factors regulate development and function of the intestinal immune system.

The Diver laboratory aims to enhance our biophysical and molecular understanding of sensory transduction and pain sensation and, specifically, how modulation of ion channels in primary afferent somatosensory neurons contributes to chronic pain.

The Farese & Walther lab studies the biology and pathology of cellular lipid metabolism, focusing on lipid/energy storage in lipid droplets and sphingolipid metabolism in lysosomes.

Lydia Finley studies the mechanisms that link metabolic pathways to cell fate decisions.

Cell biologist Hironori Funabiki focuses on regulation of the structure and configuration of chromosomes during the cell division cycle.

Physician-scientist Karuna Ganesh studies stem cell plasticity in metastasis, therapy resistance and tissue regeneration.