Research Labs

Immunologist Justin Perry investigates homeostatic apoptotic cell clearance and how this process is exploited during cancer development and progression.

The Pertsinidis laboratory uses single-molecule approaches to understand gene transcription and the function of complex macromolecular machines inside live cells.

Molecular biologist John Petrini investigates the repair of chromosomal breaks and the activation of the DNA-damage-induced cell-cycle checkpoints.

Molecular biologist Simon Powell investigates DNA replication and recombination, chromosome dynamics, and human genetics.

Molecular biologist Dirk Remus investigates mechanisms of DNA replication in eukaryotic cells.

Cell biologist Marilyn Resh investigates the regulation of protein function by fatty acylation, and the development of Hedgehog palmitoylation inhibitors to block pancreatic and lung cancer.

Immunology Program Chair Alexander Rudensky focuses on immunological tolerance and the differentiation and function of T cells.

Physician-scientist Charles Rudin focuses on the development and testing of novel therapeutic approaches to lung cancer in preclinical models.

Cell biologist Timothy Ryan studies the molecular basis of synaptic transmission in the mammalian brain.

Molecular Pharmacology Program Member David Scheinberg focuses on the discovery and development of novel, specific immunotherapeutic agents and targeted nanodevices for cancer therapy.