Combining Immunotherapy with Isolated Limb Infusion in Treating Advanced Melanoma


Surgical oncologist Charlotte Ariyan explains the standard treatment strategy for patients diagnosed with early melanoma, which can include surgical removal of the cancer.
Dr. Ariyan explains how she is leading a clinical trial with surgical oncologist Mary Sue Brady of a new treatment approach for patients with advanced disease, which combines chemotherapy and an immune system drug therapy. First, patients receive chemotherapy to an affected limb through a minimally invasive procedure known as an isolated limb infusion. Next, they receive a US Food and Drug Administration–approved immunotherapy treatment called ipilimumab (Yervoy ™).
Learn more about this clinical trial.