How Genetic Mutations Influence Cancer Risk and How Hereditary Predisposition Influences Cancer Forward arrow iconAn arrowing pointing forward, usually indicating forward movement, or the ability the share something via social media. Close iconAn icon showing an uppercase letter "X", indicating that this will close the current element. Share Facebook iconAn icon representing the Facebook social media site. Twitter iconAn icon representing the Twitter social media site. LinkedIn iconAn icon representing the social media service LinkedIn. Printer iconAn icon showing a printer, indicating the ability to print the associated media. Print Video24:00Medical oncologist Kenneth Offit explains inherited mutations, hereditary disease, and their influence on cancer.