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In the Lab

Researchers Shed Light on Why Some Breast Cancers Spread to the Lungs

By Media Staff | Friday, August 24, 2012

A new Memorial Sloan-Kettering study has identified one of the proteins fueling the spread of some breast cancers, and researchers hope their findings will lead to the development of new diagnostic tools and drugs.

Tags: Cancer Biology; Lab Research; Research; Breast Cancer

In the Lab

Study Links Cancer’s Ability to Spread with Chemotherapy Resistance

By Julie Grisham, MS, Science Writer/Editor | Friday, July 6, 2012

A team of investigators from Memorial Sloan-Kettering has shown for the first time that tumor growth, metastasis, and chemotherapy resistance are connected to the same molecular changes inside breast cancer cells.

Tags: Cancer Biology; Lab Research; Research; Cancer Genetics; Breast Cancer

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An Interview with Cancer Biologist Michael Kharas

By Eva Kiesler, PhD, Science Writer/Editor | Wednesday, April 11, 2012

As a child, Michael Kharas knew that he wanted to “be making the drugs doctors use to cure people.” Today he investigates molecular processes that stem cells and tumor cells have in common – in the hopes of uncovering insights for treatments for cancer and other diseases.

Tags: Cancer Biology; Research; Stem Cells

In the Lab

Genetic Profiling Could Help Doctors Make More-Accurate Leukemia Prognoses

By Jim Stallard, MA, Writer/Editor | Thursday, March 15, 2012

Researchers have identified a set of genetic abnormalities that can enhance prognostic accuracy and aid treatment selection for people with acute myelogenous leukemia (AML).

Tags: Cancer Biology; Lab Research; Research; Acute Myelogenous Leukemia; Cancer Genetics; Pediatric Leukemias; Personalized Medicine; Leukemias

In the Lab

Researchers Find Gene Mutations Linked to Age at Neuroblastoma Diagnosis

By Eva Kiesler, PhD, Science Writer/Editor | Tuesday, March 13, 2012

In a large-scale genome-sequencing study, researchers have discovered mutations in neuroblastoma tumors that could aid the development of diagnostic tests and therapies.

Tags: Cancer Biology; Lab Research; Research; Neuroblastoma; Cancer Genetics

In the Lab

Studies Show How Certain Gene Mutations May Promote Cancer

By Julie Grisham, MS, Science Writer/Editor | Wednesday, February 15, 2012

Two Memorial Sloan-Kettering studies provide new clues about genetic mutations that affect cell behavior and play a role in several types of cancer.

Tags: Cancer Biology; Lab Research; Research; Cancer Genetics

In the Lab

Genetic Study Identifies Mutations in Pediatric Cancers

By Jim Stallard, MA, Writer/Editor | Wednesday, February 1, 2012

Memorial Sloan-Kettering researchers have performed the first large-scale genetic analysis of several pediatric cancers, identifying mutations and potential targets for therapies to treat the cancers.

Tags: Cancer Biology; Ewing Sarcoma; Lab Research; Research; Neuroblastoma; Cancer Genetics; Pediatric Cancer Care; Personalized Medicine; Rhabdomyosarcoma

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Genetic Causes of Blood Cancers Explored

By Jim Stallard, MA, Writer/Editor | Tuesday, December 20, 2011

German-born cancer biologist Hans-Guido Wendel is taking advantage of transformative advances in genomics technology to understand key genetic abnormalities in leukemia and lymphoma.

Tags: Cancer Biology; Research; Cancer Genetics; Leukemias; Lymphomas

Pictured: Breast tumor treated with paclitaxel

In the Lab

Research Suggests New Drugs Could Boost the Effectiveness of Chemotherapy

By Eva Kiesler, PhD, Science Writer/Editor | Friday, December 2, 2011

Recent findings by Memorial Sloan-Kettering investigators suggest it might be possible to improve the effectiveness of chemotherapy for breast cancer by combining the treatment with a new type of drug called a cathepsin inhibitor.

Tags: Cancer Biology; Research; Cancer Genetics; Chemotherapy; Drug Discovery; Breast Cancer