Bladder Cancer: Prediction Tools

Our bladder cancer nomogram is an online prediction tool that can be used to calculate the chances that a patient’s bladder cancer will not have returned five years after removal of the bladder by surgery (called radical cystectomy).

Who Can Use This Tool?

This nomogram was designed for physicians and people with bladder cancer. If you are a patient, we recommend that you use this tool in consultation with your doctor.

This tool can be used to estimate the risk of cancer recurrence after radical cystectomy for localized, locally advanced, or regionally advanced primary invasive bladder cancer. This includes individuals with:

  • transitional cell carcinoma (TCC) — including TCC with elements of squamous cell carcinoma (SCC) or adenocarcinoma
  • squamous cell carcinoma only
  • pure adenocarcinoma of the bladder

This nomogram is appropriate for patients who have been treated with radical cystectomy only, either with or without removal of the lymph nodes (pelvic lymphadenectomy). Patients who received intravesical therapy prior to surgery can also use this tool.

This tool is not appropriate for patients who have received neoadjuvant chemotherapy (chemotherapy before surgery), adjuvant chemotherapy (chemotherapy after surgery), or pelvic radiation.

Why Is This Tool Useful?

Understanding the risk of bladder cancer recurrence is important because it is a key factor in deciding whether a patient requires adjuvant therapies such as chemotherapy. This nomogram can help you and your physician evaluate the best treatment plan following surgery. It can also help researchers design and evaluate clinical trials.

This nomogram, which is based on detailed information drawn from more than 9,000 bladder cancer patients treated by radical cystectomy alone at 12 centers worldwide — the largest study ever — provides a more accurate picture of the five-year risk of recurrence than older assessment tools.

What Information Will You Need?

In order for this nomogram to provide an accurate prediction, you must include accurate values for all of the information below.

  • Gender: Male or female.
  • Age: Patient's age at the time of radical cystectomy.
  • Number of days from diagnosis to radical cystectomy: Must be between 0 and 1,000.
  • Stage: According to the 1997 UICC clinical staging system: P0, PA, PIS, P1, P2, P3, or P4.
  • Histology: Type of bladder cancer (transitional cell carcinoma [TCC], squamous cell carcinoma [SCC], or adenocarcinoma (ADENO).
  • Tumor Grade: High or low.

To better understand the results of the nomogram, patients should discuss survival estimates with their doctors.

Use our bladder cancer nomogram.

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