Prostate Cancer: Our Clinical Trials

In addition to providing excellent care, Memorial Sloan-Kettering is constantly working to improve treatment for prostate cancer. Our clinical trials enable us to deliver state-of-the-art care, and our physicians lead a large number of trials of innovative approaches to treatment for men at all clinical states of prostate cancer. These trials test new drugs and drug combinations, surgical and radiation therapy techniques, innovative diagnostic technologies, and strategies for preserving quality of life for men undergoing treatment.

Choosing Memorial Sloan-Kettering for your care may give you access to new treatment options before they are widely available elsewhere. Our experts can help to determine which clinical trials are right for you. For more information about our clinical trials, call our Physician Referral Service at 800-525-2225, or talk with your doctor.

Memorial Sloan-Kettering is the coordinating center for the Prostate Cancer Clinical Trials Consortium (PCCTC), a national organization that includes 13 leading academic centers. The PCCTC is engaged in the development of new medications and new combined-modality approaches against aggressive disease that will affect lifespan or quality of life. We have long been at the forefront of bringing needed new drugs to patients quickly. Our medical oncologists have leadership positions within the consortium and other national clinical trial groups focusing on prostate cancer, and created the infrastructure for the development and evaluation of new prostate cancer drugs.

The following prostate cancer clinical trials at Memorial Sloan-Kettering are currently enrolling new patients. To learn more about a study, choose from the list below.

Showing 27 trials
Title Investigator
A Phase I Dose Escalation Study Using Ultra-Hypofractionated, Image-Guided, Intensity-Modulated Radiotherapy in Prostate Cancer
[Protocol 09-035]
Zelefsky, Michael, MD
A Phase I Study of AT13387 Alone or with Abiraterone to Treat Castration-Resistant Prostate Cancer that Continues Growing Despite Abiraterone
[Protocol 12-248]
Slovin, Susan, MD, PhD
A Phase I Study of BMS-986015 with Ipilimumab in Patients with Advanced Non-Small Cell Lung Cancer, Prostate Cancer, or Melanoma
[Protocol 12-283]
Rizvi, Naiyer, MD
A Phase I Study of DSTP3086S in Patients with Metastatic Castration-Resistant Prostate Cancer
[Protocol 11-016]
Danila, Daniel, MD
A Phase I/IIa Study of Alpharadin® Plus Docetaxel in Patients with Bone Metastases from Castration-Resistant Prostate Cancer
[Protocol 10-086]
Morris, Michael, MD
A Phase IA/B Study of CC-115 in Castration-Resistant Prostate Cancer
[Protocol 12-080]
Rathkopf, Dana, MD
A Phase II Study Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy in Low-Risk Prostate Cancer
[Protocol 11-056]
Zelefsky, Michael, MD
A Phase II Study of Abiraterone, Prednisone, and Degarelix in Men with Recurrent Prostate Cancer and a Rising PSA
[Protocol 12-187]
Scher, Howard, MD
A Phase II Study of BIND-014 in Patients with Metastatic Castration-Resistant Prostate Cancer
[Protocol 13-090]
Scher, Howard, MD
A Phase II Study of MLN8237 in Patients with Advanced Prostate Cancer
[Protocol 13-042]
Danila, Daniel, MD
A Phase III Study of Cabozantinib (XL184) versus Mitoxantrone/Prednisone in Men with Previously Treated Symptomatic Castration-Resistant Prostate Cancer
[Protocol 12-032]
Scher, Howard, MD
A Phase III Study of Cabozantinib versus Prednisone in Metastatic Castration-Resistant Prostate Cancer after Prior Treatment
[Protocol 12-274]
Rathkopf, Dana, MD
A Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer
[Protocol 07-041]
Eastham, James, MD
A Phase III Study of ProstAtakTM as an Adjuvant to Up-front Radiation Therapy for Localized Prostate Cancer
[Protocol 11-172]
Slovin, Susan, MD, PhD
A Phase III Trial of Short-Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed-Only Radiotherapy in Prostate Cancer Patients with a Rising PSA after Radical Prostatectomy
[Protocol 09-102]
Zelefsky, Michael, MD
A Pilot Study of a Geriatric-Specific Psychoeducational Intervention for Elderly Cancer Patients
[Protocol 09-116]
Roth, Andrew, MD
A Prospective Phase II Study of Brachytherapy in Men with Prostate Cancer that Returned after Prior External Beam Radiation Therapy
[Protocol 12-098]
Kollmeier, Marisa, MD
A Randomized Trial of Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy
[Protocol 09-005]
Mulhall, John, MD
A Study of Degarelix Before Prostatectomy in Patients with Intermediate- to High-Risk Prostate Cancer
[Protocol 11-182]
Rathkopf, Dana, MD
Adoptive Transfer of Autologous T Cells Targeted to Prostate-Specific Membrane Antigen for the Treatment Of Castrate Metastatic Prostate Cancer
[Protocol 09-036]
Slovin, Susan, MD, PhD
An Interactive e-Health Program to Promote Health Behaviors Among Cancer Survivors
[Protocol 12-090]
Ostroff, Jamie, PhD
Clinical Significance of Germline BRCA Mutations
[Protocol 96-051]
Offit, Kenneth, MD
Decision-Making about Active Surveillance among Prostate Cancer Patients and Their Partners/Allies
[Protocol 13-076]
Nelson, Christian, PhD
Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
[Protocol 11-112]
Zaider, Talia, PhD
Prostate Cancer Treatment Decision-Making and Survivorship
[Protocol 11-058]
Nelson, Christian, PhD
The Impact of Androgen Ablation Therapy on Cognitive Functioning and Functional Status in Men with Prostate Cancer Age 65 and Older
[Protocol 06-084]
Nelson, Christian, PhD
[18F]-Deoxy-D-Glucose (FDG) and [18F] Dihydro-Testosterone PET Imaging in Patients with Progressive Prostate Cancer
[Protocol 00-095]
Morris, Michael, MD