I currently serve as Vice Chair for Research and Chief of the Radiochemistry & Imaging Sciences Service in Memorial Sloan-Kettering's Department of Radiology, and I am Director of Memorial Sloan-Kettering's Radiochemistry and Molecular Imaging Probe Core Facility. I am a Member in Memorial Sloan-Kettering, head of a laboratory in the Sloan-Kettering Institute's Molecular Pharmacology and Chemistry Program, and a Professor at the Gerstner Sloan-Kettering Graduate School of Biomedical Sciences. I have published over 130 papers, books, book chapters, and reviews in the field of cancer imaging. I serve on grant review panels for the National Institutes of Health/National Cancer Institute and on a number editorial boards.
My research interests are focused on the development of new PET radiopharmaceuticals for the diagnosis and treatment of cancer. My work incorporates 89Zr, 18F, 11C, and other nonstandard nuclides, with an emphasis on designing novel PET agents for cancer imaging. My research program is a molecular-imaging-based program focused on the targetry of nonstandard nuclides as well as the development of small and biomolecule-based agents and their clinical translation. I have worked on the development of small molecules targeting cancer, as well as radiolabeled peptides and 89Zr-labeled antibodies targeting the overexpression of receptors and antigens on tumors. The research is supported by the National Institutes of Health, the Department of Education, and philanthropy.
I am also principle investigator (PI) of a “DOE Center of Excellence in Radiochemistry,” which supports junior faculty, postdoctoral, and graduate trainees. I am also a co-PI of an NSF IGERT grant with Hunter College of the City University of New York (CUNY) that will support 15 PhD candidates in radiochemistry.