Health Care Professional Information

Common Name

Entelev®, Cantron®, Sheridan’s formula, JS-114, JS-101, 126-F, Jim’s Juice, Quantrol, Protocel®

Clinical Summary

Unproven alternative treatment which contains a variety of ingredients depending on manufacturer (e.g catechol, nitric acid, sodium sulfite, potassium hydroxide, sulfuric acid, crocinic acid, and various minerals and vitamins). Patients use this product to prevent and treat cancer, HIV/AIDS, epilepsy, Alzheimer's, and other immunologic and degenerative diseases.
Proposed by James Sheridan in the 1930s, CanCell® is believed to balance the vibrational frequency of cancer cells, thereby returning them to their healthy state. This theory is not supported by scientific evidence (1) (2).
Manufacturers of CanCell® discourage combining CanCell® with conventional oncology treatments (1). Patients should avoid this product.

Purported Uses
  • Alzheimer's disease
  • Cancer treatment
  • Cystic fibrosis
  • Diabetes
  • Emphysema
  • Epilepsy
  • Hemophilia
  • Herpes
  • HIV and AIDS
  • Hypertension
  • Hypotension
  • Multiple sclerosis
  • Scleroderma
  • Systemic lupus erythematosus (SLE)
  • Viral infections
Constituents
  • Nitric acid
  • Sodium sulfite
  • Potassium hydroxide
  • Sulfuric acid
  • Catechol
  • Crocinic acid
  • Inositol
  • Minerals
  • Vitamins
    (1)
Mechanism of Action

Manufacturers of CanCell® and Cantron® offer different theories explaining their products' anticancer activities: Cancer cells function at a “critical point” of cellular respiration, above which normal cells function aerobically, and below which abnormal anaerobic cells are destroyed as foreign matter. The catechol component is claimed to inhibit cellular respiration in cancer cells so that they might fall from the “critical point” to a primitive state and self-destruct. In addition, CanCell® is thought to balance the vibration frequency of cancer cells, returning them to a normal state. The manufacturers of Cantron® claim that imbalance in cellular respiration results in cellular damage. Cantron® is believed to help maintain balance through the electrolyte and antioxidant properties of its hydroxyquinone and catechol components. Neither set of claims is substantiated by scientific data.
(1) (2)

Pharmacokinetics

No formal pharmacokinetics studies exist. The manufacturer states that the product is absorbed orally, sublingually, topically, and rectally.
(1)

Literature Summary and Critique

Although the manufacturers of CanCell® maintain that extensive studies in mice and humans document its efficacy (3), no data have been published in peer-reviewed journals. In 1978 and 1980, the National Cancer Institute (NCI) conducted animal studies with CanCell® and found that the product lacked antitumor activity. The NCI's In Vitro Anticancer Drug Discovery Program evaluated CanCell® in 1990-1, also with negative results (1). Neither study was published. It was determined that no further research on CanCell®/Entelev® was warranted.

References
  1. American Cancer Society. Questionable methods of cancer management: Cancell/Entelev. Ca: Cancer J Clin 1993;43:57-62.
  2. Grossgebauer K. The 'Cancell' theory of carcinogenesis: re-evolution of an ancient, holistic neoplastic unicellular concept of cancer. Med Hypotheses 1995;45:545-55.
  3. Cancell Alternative Cancer Treatment Comparison. http://alternativecancer.us/cancell.htm. Accessed September 5, 2013.

Consumer Information

How It Works

Bottom Line: Cancell® has not been shown to treat or prevent cancer.

CanCell® (also called Entelev® or Cantron®) was developed by a chemist in the 1930s. Its exact ingredients are unknown, but it is thought to contain catechol (stabilizes collagen and is used in tanning and dyeing), nitric acid (an intermediate used in the manufacturing of fertilizers and explosives), sodium sulfite, potassium hydroxide (a caustic material), sulfuric acid (a corrosive liquid), crocinic acid, and various minerals and vitamins. This mixture of chemicals, the manufacturers claim, normalizes the cellular metabolism and balances the vibration frequency of cancer cells, causing them to die or return to a healthy state. Scientists from the National Cancer Institute reviewed these theories, tested CanCell® in laboratory studies on cancer cells, and concluded that CanCell® has no anticancer activity.
 

Purported Uses

None of the following claims is supported by scientific evidence.

  • To treat Alzheimer's disease
  • To treat cancer
  • To treat cystic fibrosis
  • To treat Diabetes
  • To treat emphysema
  • To treat epilepsy
  • To treat Epstein-Barr virus
  • To treat hemophilia
  • To treat herpes
  • To treat HIV and AIDS
  • To lower high blood pressure
  • To raise low blood pressure
  • To treat multiple sclerosis
  • To treat scleroderma
  • To treat systemic lupus erythematosus (SLE)
Research Evidence

Although the manufacturers of CanCell® claim that extensive studies in mice and humans show that it is effective, none of these studies have been published in peer-reviewed journals. In 1978 and 1980, the National Cancer Institute (NCI) conducted animal studies with CanCell® and found that the product lacked antitumor activity. The NCI's In Vitro Anticancer Drug Discovery Program evaluated CanCell® in 1990-1, also with negative results. It was determined that no further research on CanCell®/Entelev® was warranted.

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