Non-Hodgkin's lymphoma can arise in lymphatic tissues almost anywhere in the body, and symptoms depend on its location. If lymphoma develops in lymph nodes close to the skin in the neck, underarms, and groin, patients may experience a persistent, painless swelling of those nodes. If lymphoma occurs in the stomach or intestines, they may have gastrointestinal bleeding, a feeling of fullness, or abdominal swelling. Disease arising in the central nervous system can cause neurological symptoms such as partial paralysis, seizures, confusion, and memory loss. Lymphoma in the chest can cause coughing, shortness of breath, and chest discomfort.
Lymph nodes swell for many reasons, most often as a result of an infection. Swollen lymph nodes are usually not caused by lymphoma. Physicians may treat a patient who has a persistent swelling with antibiotics. If this treatment does not reduce the swelling, the physician may order a biopsy of the swollen node.
Other generalized symptoms of lymphoma include fever, fatigue, night sweats, unexpected weight loss, and itchy skin. Like swollen lymph nodes, these symptoms are associated with a wide range of conditions and illnesses; medical evaluation can determine if they might be caused by lymphoma.
