Dr. Mellinghoff received his medical degree from the Technical University Munich. He then moved to the University of California, Los Angeles, where he completed residency training in Internal Medicine and subspecialty training in Hematology-Oncology. Following a research fellowship in the laboratory of Dr. Charles Sawyers, he joined the faculty of the UCLA Department of Molecular and Medical Pharmacology and the Crump Institute for Molecular Imaging. In the fall of 2007, Dr. Mellinghoff moved from UCLA to Memorial Sloan-Kettering Cancer Center to join the Human Oncology and Pathogenesis Program and the Department of Neurology. Dr. Mellinghoff's research program focuses on the development of new diagnostic and therapeutic approaches for cancer with a particular disease focus on glioblastoma.