Cracking the Cancer Code An interview with Dr. Kenneth Offit, Chief of the Clinical Genetics Service 
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The Role of Genes
Everyone has some chance of developing cancer. Most cancer cases occur sporadically or by chance. However, some people may develop cancer due to alterations in hereditary factors called genes. Hereditary cancer is the development of cancer due to an inherited gene mutation (changes in a specific gene) that has been passed from a parent to a child upon conception. If a person has inherited such a gene mutation, he or she has inherited an increased risk to develop cancer in their lifetime, which is higher than the cancer risk of someone in the general population.
Over the past decade, scientists have discovered specific genes that can contribute to the development of hereditary breast, ovarian, colorectal, and other less common cancers. Genetic testing is now available for some of these types of hereditary cancers. People who are interested in learning whether or not they have an increased likelihood of developing certain cancers or whether they inherited a gene that contributed to their own or a family member's cancer should consult with a specialist with experience in the area of hereditary cancer, cancer risk assessment, and genetic counseling and testing.
Genetic Counseling
Genetic counseling involves a discussion of your personal and/or family history of cancer. Genetic counselors will simplify complex scientific concepts into terms you can understand. The goal of cancer genetic counseling is to provide clear and clinically relevant information about genetic risk factors in an atmosphere of support and education.
Genetic counseling is typically recommended for individuals or families with multiple cases of cancer diagnosed at unusually young ages.
Genetic Testing
Genetic testing involves the use of laboratory methods to obtain a more precise estimate of your cancer risk. Although a cancer risk assessment can be provided without genetic testing, in some cases testing may help you and your physician make important decisions about your medical care. Deciding whether or not to undergo genetic testing is a personal choice that can be made at the time of the counseling session or at a future date.
Genetic counseling does not require genetic testing. Genetic testing may not be useful for everyone receiving genetic counseling.
