Research Labs

Physician-scientist Yu Chen studies the role of transcription factors that are critical for prostate cancer development.

The Choi Lab develops new synthetic biology tools to study cell-fate decisions in development.

Lydia Finley studies the mechanisms that link metabolic pathways to cell fate decisions.

Physician-scientist Karuna Ganesh studies stem cell plasticity in metastasis, therapy resistance and tissue regeneration.

The Gladkova lab studies the mechanisms and signals that reshape cellular organelle architecture in response to physiological stimuli.

The Hadjantonakis laboratory studies pluripotency and cell fate specification, tissue patterning and morphogenesis, in mammalian embryos and stem cell-derived embryo models.

Physician-scientist Alan Hanash studies transplant immunology and immune-mediated mechanisms of tissue damage and regeneration.

The Huangfu laboratory uses human pluripotent stem cells (hPSCs) as a powerful genetic model to interrogate the transcriptional and epigenetic mechanisms underlying cell fate decisions in development and disease.

The Jasin laboratory focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.

Cancer biologist Michael Kharas studies RNA regulators of self-renewal in both normal and leukemic hematopoiesis.