Human Oncology & Pathogenesis Program
Physician-scientist Scott Armstrong focuses on defining genetic and epigenetic programs that control the extensive self-renewal properties associated with leukemia and other cancers.
Physician-in-Chief, Memorial Hospital
Human Oncology & Pathogenesis Program
Memorial Sloan-Kettering Physician-in-Chief José Baselga studies mechanisms of resistance to targeted therapies and identification of novel therapeutic combinations in solid cancers.
Cancer Biology & Genetics Program
Cancer biologist Robert Benezra studies the molecular mechanisms of tumor growth and progression using mouse Id1 and Id3 knockout models and analysis of the spindle assembly checkpoint.
Developmental Biology Program
Developmental biologist Peter Besmer focuses on normal and oncogenic receptor tyrosine kinase signaling in vitro and in vivo in mice.
Molecular Pharmacology & Chemistry Program
Physician-scientist Ronald Blasberg focuses on the development of noninvasive imaging paradigms in living organisms using radionuclide and optical reporter systems.
Memorial Hospital Research Laboratories
Clinician-scientist Michelle Bradbury develops translational, tumor-targeting, PET-optical silica nanoparticle probes for diagnostics, drug delivery, and sensing.
Memorial Hospital Research Laboratories
Physician-scientist Renier Brentjens develops novel immunotherapies for leukemias and lymphomas.
Memorial Hospital Research Laboratories
Physician-scientist Jacqueline Bromberg focues on aberrantly activated Stat3 and the mechanisms of Stat3-mediated transformation.
Memorial Hospital Research Laboratories
Physician-scientist Jorge Carrasquillo focuses on the development of targeted radioimmunotherapy drugs.
Molecular Pharmacology & Chemistry Program
Molecular biologist Luca Cartegni investigates the role of alternative splicing events in the development or maintenance of cancer.
Memorial Hospital Research Laboratories
Physician-scientist Brett Carver focuses on the identification of molecular pathways involved in prostate cancer initiation and progression.
Human Oncology & Pathogenesis Program
Physician-scientist Sarat Chandarlapaty studies the regulation of growth factor signaling networks in cancer.
Human Oncology & Pathogenesis Program
Physician-scientist Yu Chen studies the role of transcription factors that are critical for prostate cancer development.
Memorial Hospital Research Laboratories
Physician-scientist Nai-Kong Cheung focuses on engineering of antibodies and immune cells to treat solid tumors in children.
Human Oncology & Pathogenesis Program
Physician-scientist Ping Chi studies genetic and epigenetic mechanisms of transcriptional regulation by oncogenic transcription factors in GIST and other solid tumors.
Molecular Pharmacology & Chemistry Program
Chemical biologist Gabriela Chiosis studies the pharmacological modulation of molecular chaperones in transformed systems.
Molecular Pharmacology & Chemistry Program
Chemical biologist Bayard Clarkson focuses on the development of targeted therapies aimed at cancer stem cells.
Molecular Pharmacology & Chemistry Program
Samuel Danishefsky investigates the synthesis of antitumor natural products and of fully synthetic carbohydrate-based vaccines.
Memorial Hospital Research Laboratories
Physician-scientist Ronald DeMatteo focuses on strategies to reduce immune subversion in gastrointestinal stromal tumor and liver cancer and on immunobiology in liver cancer.
Memorial Hospital Research Laboratories
Physician-scientist Liang Deng studies poxvirus interface with the immune system and the development of poxviruses as oncolytic and immunotherapy for cancers.
Human Oncology & Pathogenesis Program
Physician-scientist James Fagin focuses on the pathogenesis of thyroid cancer and the role of oncogenic kinases.
Memorial Hospital Research Laboratories
Physician-scientist Yuman Fong develops herpes-based oncolytic viral therapies for the treatment of malignancy.
Molecular Pharmacology & Chemistry Program
Zvi Fuks studies mechanisms of radiation-induced damage and the clinical basis of radiation resistance.
Molecular Pharmacology & Chemistry Program
Chemist Daniel Heller focuses on biomaterials and nanoscale engineering for molecular sensors and targeted therapeutics.
Cancer Biology & Genetics Program
Physician-scientist Eric Holland focuses on the molecular mechanisms underlying the pathogenesis of CNS tumors and modeling of these cancers in the mouse.
Immunology Program
Cancer immunologist Alan Houghton studies the immune response to cancer, immune recognition of self and mutated molecules, and development of new immunotherapies.
Human Oncology & Pathogenesis Program
Physician-scientist James Hsieh focuses on the development of novel therapeutics targeting cancer cell proliferation and establishment of a translational kidney cancer program.
Human Oncology & Pathogenesis Program
Physician-scientist Jason Huse focuses on the molecular pathogenesis of brain tumors, particularly high-grade gliomas.
Developmental Biology Program
Developmental biologist Maria Jasin focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
Cancer Biology & Genetics Program
Cancer biologist Johanna Joyce investigates the signaling pathways between cancer cells and their microenvironment in tumor progression, metastasis, and response to therapy.
Molecular Pharmacology & Chemistry Program
Physician-scientist Richard Kolesnick studies the role of ceramide signaling in radiation-induced vascular dysfunction and tumor regression.
Memorial Hospital Research Laboratories
Physician-scientist Jason Koutcher studies applications of magnetic resonance spectroscopy and imaging to enhance the therapeutic gain of different antineoplastic modalities.
Molecular Pharmacology & Chemistry Program
Radiologist Steven Larson focuses on molecular imaging in animals and humans using high-resolution diagnostic instruments, such as positron emission tomography, and single photon emission tomography.
Memorial Hospital Research Laboratories
Physician-scientist Douglas Levine studies the genomic basis for prevention and control of ovarian and uterine carcinomas.
Memorial Hospital Research Laboratories
Radiochemist Jason Lewis develops radiopharmaceuticals for the imaging and therapy of cancer.
Memorial Hospital Research Laboratories
Radiation scientist Gloria Li studies the response of cells to stressors such as heat and radiation.
Immunology Program
Immunologist Ming Li studies the mechanisms of T Cell homeostasis, tolerance, and immunity, and their relevance to autoimmune diseases and cancer.
Molecular Pharmacology & Chemistry Program
Biochemist Yueming Li studies function and regulation of transmembrane proteases and development of novel protease-based cancer therapies.
Molecular Pharmacology & Chemistry Program
Imaging specialist Clifton Ling focuses on the study and noninvasive imaging of tumor hypoxia.
Memorial Hospital Research Laboratories
Physician-scientist Philip Livingston studies tumor vaccinology, including approaches to augmenting the antibody and T cell response to defined cancer antigens.
Structural Biology Program
Structural biologist Stephen Long studies the structural biology of ion channels and enzymatic membrane proteins.
Chair, Geoffrey Beene Cancer Research Center
Cancer Biology & Genetics Program
Biologist Scott Lowe investigates tumor-suppressor gene networks that control apoptosis and senescence.
Molecular Pharmacology & Chemistry Program
Chemist Minkui Luo develops chemical tools to elucidate protein-posttranslational modification and designs inhibitors for cancer therapies.
Cell Biology Program
Cell biologist Paul Marks focuses on the study of agents that selectively target histone deacetylases and cause transformed cell growth arrest, terminal differentiation, apoptosis, and/or cell death.
Chair, Cancer Biology & Genetics Program, SKI
Cancer Biology & Genetics Program
Cancer Biology & Genetics Program Chair Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
Cell Biology Program
Cell biologist Malcolm Moore focuses on the characterization of normal and cancer stem cells and the development of selective therapies.
Immunology Program
Physician-scientist Richard O'Reilly investigates the genetic disparities and cellular interactions between donor and host that affect allogeneic hematopoietic cell transplantation.
Memorial Hospital Research Laboratories
Physician-scientst Ying-Xian Pan studies the transcription regulation and function of opioid receptor genes.
Human Oncology & Pathogenesis Program
Physician-scientist Christopher Park focuses on the identification and characterization of molecular pathways that regulate normal and malignant stem cells in the hematopoietic system.
Molecular Pharmacology & Chemistry Program
Pharmacologist Gavril Pasternak studies molecular mechanisms of opioid receptor actions, analgesics, and G-protein-coupled receptors.
Memorial Hospital Research Laboratories
Physician-scientist Vladimir Ponomarev focuses on developing reporter genetic systems for specific applications such as sequential in vivo imaging studies in cancer biology, cancer immunotherapy, and radiation sciences.
Memorial Hospital Research Laboratories
Physician-scientist Shyam Rao studies the role of the tumor microenvironment in tumorigenesis and response to radiation therapy.
Molecular Pharmacology & Chemistry Program
Pharmacologist Neal Rosen focuses on understanding biochemical mechanisms underlying phenotypes caused by tyrosine kinase activation in epithelial tumors and developing new therapeutic strategies.
Molecular Pharmacology & Chemistry Program
Immunologist Michel Sadelain studies the mechanisms governing transgene expression, stem cell engineering, and genetic strategies to enhance immunity against cancer.
Chair, Human Oncology and Pathogenesis Program
Human Oncology & Pathogenesis Program
Human Oncology and Pathogenesis Program Chair Charles Sawyers develops molecularly targeted cancer therapy.
Chair, Molecular Pharmacology & Chemistry Program, SKI
Molecular Pharmacology & Chemistry Program
Molecular Pharmacology and Chemistry Program Chair David Scheinberg focuses on the discovery and development of novel, specific immunotherapeutic agents and targeted nanodevices for cancer therapy.
Memorial Hospital Research Laboratories
Physician-scientist Gary Schwartz focuses on the identification of cell-cycle inhibitors that promote chemotherapy-induced apoptosis and their use in cancer therapy.
Molecular Biology Program
Molecular biologist Stewart Shuman studies mechanisms and structures of the mRNA cap-forming enzymes and the means by which capping is coupled to transcription.
Memorial Hospital Research Laboratories
Physician-scientist Samuel Singer studies the genomic alterations that define new targets for therapy in sarcoma.
Human Oncology & Pathogenesis Program
Physician-scientist David Solit studies human oncology and pathogenesis, genomics, oncogenes and tumor suppressors, cancer therapeutics, and clinical trials.
Memorial Hospital Research Laboratories
Physician-scientist David Spriggs studies the molecular mechanisms of drug resistance in ovarian cancer.
Memorial Hospital Research Laboratories
Physician-scientist Viviane Tabar focuses on in vivo applications of neural derivatives of pluripotent stem cells (such as iPS and ES cells) and on cancer stem cells in human brain tumors.
Molecular Pharmacology & Chemistry Program
Chemist Derek Tan studies diversity-oriented synthesis and rational drug design for chemical biology and drug discovery.
Immunology Program
Physician-scientist Marcel R. M. van den Brink studies the immunology of bone marrow transplantation.
Computational Biology Program
Computational biologist Harel Weinstein investigates the structural, dynamic, and integrative determinants of molecular and cellular mechanisms underlying physiological function and pharmacological activity.
Memorial Hospital Research Laboratories
Physician-scientist Martin Weiser investigates the mechanisms underlying tumor spread and metastasis and how these mechanisms could be targeted.
Cancer Biology & Genetics Program
Cancer biologist Hans-Guido Wendel focuses on modeling the genetics of tumor initiation, progression, and treatment response in vivo.
Cancer Biology & Genetics Program
Cancer biologist Richard Mark White investigates the evolution of metastases in zebrafish.
Immunology Program
Physician-scientist Jedd Wolchok investigates novel approaches for cancer immunotherapy and mechanisms of tumor cell–immune cell interactions.
Memorial Hospital Research Laboratories
Physician-scientist Richard Wong studies the mechanisms of cancer cell chemotaxis in perineural invasion.
Memorial Hospital Research Laboratories
Physician-scientist Sam Yoon studies the role of tumor microenvironment in the progression and radiation response of sarcomas and gastric cancer.
