Find Faculty & Laboratory Staff

A

Adusumilli, Prasad S.
Memorial Hospital Research Laboratories
Physician-scientist Prasad Adusumilli studies tumor immunology and the development of T-cell-mediated immunotherapy for thoracic malignancies and pleural-based diseases.
Scott Armstrong
Armstrong, Scott A.
Director, Leukemia Center
Cancer Biology & Genetics Program
Physician-scientist Scott Armstrong focuses on defining genetic and epigenetic programs that control the extensive self-renewal properties associated with leukemia and other cancers.

B

Baselga, José
Physician-in-Chief, Memorial Hospital
Human Oncology & Pathogenesis Program
Memorial Sloan Kettering Physician-in-Chief José Baselga studies mechanisms of resistance to targeted therapies and identification of novel therapeutic combinations in solid cancers.
Pictured: Robert Benezra
Benezra, Robert
Cancer Biology & Genetics Program
Cancer biologist Robert Benezra studies the molecular mechanisms of tumor growth and progression using mouse Id1 and Id3 knockout models and analysis of the spindle assembly checkpoint.
Pictured: Peter Besmer
Besmer, Peter
Developmental Biology Program
Developmental biologist Peter Besmer focuses on normal and oncogenic receptor tyrosine kinase signaling in vitro and in vivo in mice.
Pictured: Ronald Blasberg
Blasberg, Ronald G.
Molecular Pharmacology & Chemistry Program
Physician-scientist Ronald Blasberg focuses on the development of noninvasive imaging paradigms in living organisms using radionuclide and optical reporter systems.
Pictured: Michelle Bardbury
Bradbury, Michelle S.
Memorial Hospital Research Laboratories
Clinician-scientist Michelle Bradbury develops translational, tumor-targeting, PET-optical silica nanoparticle probes for diagnostics, drug delivery, and sensing.
Pictured: Renier J. Brentjens
Brentjens, Renier J.
Director, Cellular Therapeutics
Memorial Hospital Research Laboratories
Physician-scientist Renier Brentjens develops novel immunotherapies for leukemias and lymphomas.
Bromberg, Jacqueline
Memorial Hospital Research Laboratories
Physician-scientist Jacqueline Bromberg focuses on aberrantly activated Stat3 and the mechanisms of Stat3-mediated transformation.

C

Pictured: Jorge A. Carrasquillo
Carrasquillo, Jorge A.
Memorial Hospital Research Laboratories
Physician-scientist Jorge Carrasquillo focuses on the development of targeted radioimmunotherapy drugs.
Pictured: Brett S. Carver
Carver, Brett S.
Memorial Hospital Research Laboratories
Physician-scientist Brett Carver focuses on the identification of molecular pathways involved in prostate cancer initiation and progression.
Pictured: Sarat Chandarlapaty
Chandarlapaty, Sarat
Human Oncology & Pathogenesis Program
Physician-scientist Sarat Chandarlapaty studies the regulation of growth factor signaling networks in cancer.
Pictured: Yu Chen
Chen, Yu
Human Oncology & Pathogenesis Program
Physician-scientist Yu Chen studies the role of transcription factors that are critical for prostate cancer development.
Cheung, Nai-Kong V.
Memorial Hospital Research Laboratories
Physician-scientist Nai-Kong Cheung focuses on engineering of antibodies and immune cells to treat solid tumors in children.
Pictured: Ping Chi
Chi, Ping
Human Oncology & Pathogenesis Program
Physician-scientist Ping Chi studies genetic and epigenetic mechanisms of transcriptional regulation by oncogenic transcription factors in GIST and other solid tumors.
Pictured: Gabriela Chiosis
Chiosis, Gabriela
Molecular Pharmacology & Chemistry Program
Chemical biologist Gabriela Chiosis studies the pharmacological modulation of molecular chaperones in transformed systems.
Pictured: Bayard Clarkson
Clarkson, Bayard
Molecular Pharmacology & Chemistry Program
Chemical biologist Bayard Clarkson focuses on the development of targeted therapies aimed at cancer stem cells.

D

Pictured: Samuel Danishefsky
Danishefsky, Samuel
Molecular Pharmacology & Chemistry Program
Samuel Danishefsky investigates the synthesis of antitumor natural products and of fully synthetic carbohydrate-based vaccines.
DeMatteo, Ronald
Memorial Hospital Research Laboratories
Physician-scientist Ronald DeMatteo focuses on strategies to reduce immune subversion in gastrointestinal stromal tumor and liver cancer and on immunobiology in liver cancer.
Pictured: Liang Deng
Deng, Liang
Memorial Hospital Research Laboratories
Physician-scientist Liang Deng studies poxvirus interface with the immune system and the development of poxviruses as oncolytic and immunotherapy for cancers.

F

Pictured: James Fagin
Fagin, James A.
Human Oncology & Pathogenesis Program
Physician-scientist James Fagin focuses on the pathogenesis of thyroid cancer and the role of oncogenic kinases.
Pictured: Zvi Fuks
Fuks, Zvi
Molecular Pharmacology & Chemistry Program
Zvi Fuks studies mechanisms of radiation-induced damage and the clinical basis of radiation resistance.

H

Daniel Heller
Heller, Daniel A.
Molecular Pharmacology & Chemistry Program
Chemist Daniel Heller focuses on biomaterials and nanoscale engineering for molecular sensors and targeted therapeutics.
Pictured: Alan Houghton
Houghton, Alan
Immunology Program
Cancer immunologist Alan Houghton studies the immune response to cancer, immune recognition of self and mutated molecules, and development of new immunotherapies.
Pictured: James J. Hsieh
Hsieh, James J.
Human Oncology & Pathogenesis Program
Physician-scientist James Hsieh focuses on developing novel therapeutics targeting cancer cell proliferation; he also directs Memorial Sloan Kettering’s translational kidney cancer research program.
Pictured: Jason T. Huse
Huse, Jason T.
Human Oncology & Pathogenesis Program
Physician-scientist Jason Huse focuses on the molecular pathogenesis of brain tumors, particularly high-grade gliomas.

J

Pictured: Maria Jasin
Jasin, Maria
Developmental Biology Program
Developmental biologist Maria Jasin focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
Pictured: Johanna Joyce
Joyce, Johanna
Cancer Biology & Genetics Program
Cancer biologist Johanna Joyce investigates the signaling pathways between cancer cells and their microenvironment in tumor progression, metastasis, and response to therapy.

K

Pictured: Alex Kentsis
Kentsis, Alex
Molecular Pharmacology & Chemistry Program
Cancer biologist and pediatric oncologist Alex Kentsis leads research in the functional proteomics and genomic plasticity of refractory childhood cancers.
Pictured: Kayvan R. Keshari
Keshari, Kayvan R.
Memorial Hospital Research Laboratories
Biochemist and imaging specialist Kayvan Keshari explores changes in cancer metabolism to develop advanced imaging techniques and cancer targets.
Pictured: Richard Kolesnick
Kolesnick, Richard N.
Molecular Pharmacology & Chemistry Program
Physician-scientist Richard Kolesnick studies the role of ceramide signaling in radiation-induced vascular dysfunction and tumor regression.
Koutcher, Jason A.
Memorial Hospital Research Laboratories
Physician-scientist Jason Koutcher studies applications of magnetic resonance spectroscopy and imaging to enhance the therapeutic gain of different antineoplastic modalities.

L

Larson, Steven M.
Molecular Pharmacology & Chemistry Program
Radiologist Steven Larson focuses on molecular imaging in animals and humans using high-resolution diagnostic instruments, such as positron emission tomography, and single photon emission tomography.
Pictured: Steven D. Leach, MD
Leach, Steven D.
Director, David M. Rubenstein Center for Pancreatic Cancer Research
Memorial Hospital Research Laboratories
Cancer Therapeutics & Drug Discovery, Cell Biology, Genetics & Genomics, Stem Cell Biology
Pictured: Douglas Levine
Levine, Douglas A.
Memorial Hospital Research Laboratories
Physician-scientist Douglas Levine studies the genomic basis for prevention and control of ovarian and uterine carcinomas.
Pictured: Jason Lewis
Lewis, Jason S.
Director, Center for Molecular Imaging and Nanotechnology
Memorial Hospital Research Laboratories
Radiochemist Jason Lewis develops radiopharmaceuticals for the imaging and therapy of cancer.
Li, Gloria C.
Memorial Hospital Research Laboratories
Radiation scientist Gloria Li studies the response of cells to stressors such as heat and radiation.
Pictured: Ming Li
Li, Ming
Immunology Program
Immunologist Ming Li studies mechanisms of immune regulation, and their relevance to diseases including cancer.
Pictured: Yueming Li
Li, Yueming
Molecular Pharmacology & Chemistry Program
Biochemist Yueming Li studies function and regulation of transmembrane proteases and development of novel protease-based cancer therapies.
Pictured: Stephen B. Long, PhD
Long, Stephen B.
Structural Biology Program
Stephen Long studies the mechanisms of ion channels and enzymatic membrane proteins.
Pictured: Scott Lowe
Lowe, Scott W.
Chair, Cancer Biology & Genetics Program, SKI; Chair, Geoffrey Beene Cancer Research Center
Cancer Biology & Genetics Program
Biologist Scott Lowe investigates tumor-suppressor gene networks that control apoptosis and senescence.
Luo, Minkui
Molecular Pharmacology & Chemistry Program
Chemist Minkui Luo develops and implements the combined chemical and biological tools to define and manipulate epigenetic functions of protein methyltransferases for disease diagnosis and therapy.

M

Pictured: Paul Marks
Marks, Paul A.
Cell Biology Program
Cell biologist Paul Marks focuses on the study of agents that selectively target histone deacetylases and cause transformed cell growth arrest, terminal differentiation, apoptosis, and/or cell death.
Pictured: Joan Massagué
Massagué, Joan
Director, Sloan Kettering Institute
Cancer Biology & Genetics Program
Sloan Kettering Institute Director Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
Pictured: Malcolm Moore
Moore, Malcolm A. S.
Cell Biology Program
Cell biologist Malcolm Moore focuses on the characterization of normal and cancer stem cells and the development of selective therapies.

O

Pictured: Richard O'Reilly
O'Reilly, Richard J.
Immunology Program
Physician-scientist Richard O'Reilly investigates the genetic disparities and cellular interactions between donor and host that affect allogeneic hematopoietic cell transplantation.

P

Ying-Xian Pan
Pan, Ying-Xian
Memorial Hospital Research Laboratories
Physician-scientst Ying-Xian Pan studies the transcription regulation and function of opioid receptor genes.
Pictured: Christopher Park
Park, Christopher Y.
Human Oncology & Pathogenesis Program
Physician-scientist Christopher Park focuses on the identification and characterization of molecular pathways that regulate normal and malignant stem cells in the hematopoietic system.
Pictured: Gavril W. Pasternak
Pasternak, Gavril W.
Molecular Pharmacology & Chemistry Program
Pharmacologist Gavril Pasternak studies molecular mechanisms of opioid receptor actions, analgesics, and G-protein-coupled receptors.
Pictured: Vladimir Ponomarev
Ponomarev, Vladimir
Memorial Hospital Research Laboratories
Physician-scientist Vladimir Ponomarev focuses on developing reporter genetic systems for specific applications such as sequential in vivo imaging studies in cancer biology, cancer immunotherapy, and radiation sciences.

R

Pictured: Govind Ragupathi
Ragupathi, Govind
Memorial Hospital Research Laboratories
Physician-scientist Govind Ragupathi studies tumor vaccinology, including approaches to augmenting the antibody and T cell response to defined cancer antigens.
Pictured: Shyam Rao
Rao, Shyam S.
Memorial Hospital Research Laboratories
Physician-scientist Shyam Rao studies the role of the tumor microenvironment in tumorigenesis and response to radiation therapy.
Pictured: Thomas Reiner
Reiner, Thomas
Memorial Hospital Research Laboratories
Imaging specialist Thomas Reiner focuses on the development of novel imaging probes for both PET imaging and optical imaging technologies.
Pictured: Neal Rosen
Rosen, Neal
Molecular Pharmacology & Chemistry Program
Pharmacologist Neal Rosen focuses on understanding biochemical mechanisms underlying phenotypes caused by tyrosine kinase activation in epithelial tumors and developing new therapeutic strategies.
Pictured: Charles Rudin
Rudin, Charles M.
Memorial Hospital Research Laboratories
Physician-scientist Charles Rudin focuses on the development and testing of novel therapeutic approaches to lung cancer in preclinical models.

S

Pictured: Michel Sadelain
Sadelain, Michel
Director, Center for Cell Engineering
Immunology Program
Immunologist Michel Sadelain studies the mechanisms governing transgene expression, stem cell engineering, and genetic strategies to enhance immunity against cancer.
Sawyers, Charles L.
Chair, Human Oncology and Pathogenesis Program
Human Oncology & Pathogenesis Program
Human Oncology and Pathogenesis Program Chair Charles Sawyers develops molecularly targeted cancer therapy.
Scheinberg, David A.
Chair, Molecular Pharmacology & Chemistry Program, SKI; Director, Center for Experimental Therapeutics
Molecular Pharmacology & Chemistry Program
Molecular Pharmacology and Chemistry Program Chair David Scheinberg focuses on the discovery and development of novel, specific immunotherapeutic agents and targeted nanodevices for cancer therapy.
Shuman, Stewart
Molecular Biology Program
Molecular biologist Stewart Shuman studies mechanisms and structures of the mRNA cap-forming enzymes and the means by which capping is coupled to transcription.
Pictured: Samuel Singer
Singer, Samuel
Memorial Hospital Research Laboratories
Physician-scientist Samuel Singer studies the genomic alterations that define new targets for therapy in sarcoma.
Pictured: David Solit
Solit, David B.
Director, Marie-Josée & Henry R. Kravis Center for Molecular Oncology
Human Oncology & Pathogenesis Program
Physician-scientist David Solit studies human oncology and pathogenesis, genomics, oncogenes and tumor suppressors, cancer therapeutics, and clinical trials.
Pictured: David Spriggs
Spriggs, David R.
Memorial Hospital Research Laboratories
Physician-scientist David Spriggs studies the molecular mechanisms of drug resistance in ovarian cancer.

T

Pictured: Viviane Tabar
Tabar, Viviane
Memorial Hospital Research Laboratories
Physician-scientist Viviane Tabar focuses on in vivo applications of neural derivatives of pluripotent stem cells (such as iPS and ES cells) and on cancer stem cells in human brain tumors.
Derek Tan, research lab head
Tan, Derek
Molecular Pharmacology & Chemistry Program
Chemist Derek Tan studies diversity-oriented synthesis and rational drug design for chemical biology and drug discovery.

V

Pictured: Marcel R. M. van den Brink
van den Brink, Marcel R. M.
Immunology Program
Physician-scientist Marcel R. M. van den Brink studies the immunology of bone marrow transplantation.

W

Pictured: Wolfgang Weber
Weber, Wolfgang A.
Chief, Molecular Imaging and Therapy Service
Memorial Hospital Research Laboratories
Physician-scientist Wolfgang Weber specializes in imaging and therapy, with a focus on the translation of novel drugs, imaging agents, and methodologies from bench to bedside.
Weinstein, Harel
Computational Biology Program
Computational biologist Harel Weinstein investigates the structural, dynamic, and integrative determinants of molecular and cellular mechanisms underlying physiological function and pharmacological activity.
Pictured: Martin R. Weiser
Weiser, Martin R.
Memorial Hospital Research Laboratories
Physician-scientist Martin Weiser investigates the mechanisms underlying tumor spread and metastasis and how these mechanisms could be targeted.
Pictured: Hans-Guido Wendel
Wendel, Hans-Guido
Associate Member
Cancer Biology & Genetics Program
Cancer biologist Hans-Guido Wendel focuses on modeling the genetics of tumor initiation, progression, and treatment response in vivo.
Pictured: Richard White
White, Richard Mark
Cancer Biology & Genetics Program
Cancer biologist Richard Mark White investigates the evolution of metastases in zebrafish.
Pictured: Jedd Wolchok
Wolchok, Jedd D.
Immunology Program
Physician-scientist Jedd Wolchok investigates novel approaches for cancer immunotherapy and mechanisms of tumor cell–immune cell interactions.
Pictured: Richard Wong
Wong, Richard J.
Memorial Hospital Research Laboratories
Physician-scientist Richard Wong studies the mechanisms of cancer cell chemotaxis in perineural invasion.

Y

Pictured: Sam Yoon
Yoon, Sam S.
Memorial Hospital Research Laboratories
Physician-scientist Sam Yoon studies the role of tumor microenvironment in the progression and radiation response of sarcomas and gastric cancer.