Computational Biology Program
Computational biologist Grégoire Altan-Bonnet focuses on probing and testing the integration of cellular activation that makes up the immune response.
Chair, Developmental Biology Program, SKI
Developmental Biology Program
Developmental Biology Program Chair Kathryn Anderson studies genetic pathways that direct embryonic patterning and morphogenesis in the mouse embryo.
Memorial Hospital Research Laboratories
Physician-scientist Cristina Antonescu studies the molecular pathogenesis of soft tissue sarcomas and gastrointestinal stromal tumors.
Human Oncology & Pathogenesis Program
Physician-scientist Scott Armstrong focuses on defining genetic and epigenetic programs that control the extensive self-renewal properties associated with leukemia and other cancers.
Developmental Biology Program
Developmental biologist Zhirong Bao investigates how the genome dictates development using C. elegans as a model.
Developmental Biology Program
Developmental biologist Mary Baylies studies the mechanisms underlying the specification and morphogenesis of muscle during development and disease.
Developmental Biology Program
Developmental biologist Peter Besmer focuses on normal and oncogenic receptor tyrosine kinase signaling in vitro and in vivo in mice.
Molecular Pharmacology & Chemistry Program
Physician-scientist Ronald Blasberg focuses on the development of noninvasive imaging paradigms in living organisms using radionuclide and optical reporter systems.
Human Oncology & Pathogenesis Program
Physician-scientist Cameron Brennan focuses on genomic analysis of human and mouse gliomas and medulloblastomas.
Cell Biology Program
Geneticist Raju Chaganti studies genomic instability in cancer cells and its implications for clinical behavior of tumors and normal cellular developmental pathways.
Human Oncology & Pathogenesis Program
Physician-scientist Sarat Chandarlapaty studies the regulation of growth factor signaling networks in cancer.
Human Oncology & Pathogenesis Program
Physician-scientist Yu Chen studies the role of transcription factors that are critical for prostate cancer development.
Human Oncology & Pathogenesis Program
Physician-scientist Emily Cheng focuses on the molecular mechanisms of cell death and their implications in tumorigenesis and cancer therapy.
Human Oncology & Pathogenesis Program
Physician-scientist Ping Chi studies genetic and epigenetic mechanisms of transcriptional regulation by oncogenic transcription factors in GIST and other solid tumors.
Molecular Pharmacology & Chemistry Program
Chemical biologist Bayard Clarkson focuses on the development of targeted therapies aimed at cancer stem cells.
Memorial Hospital Research Laboratories
Physician-scientist Liang Deng studies poxvirus interface with the immune system and the development of poxviruses as oncolytic and immunotherapy for cancers.
Human Oncology & Pathogenesis Program
Physician-scientist James Fagin focuses on the pathogenesis of thyroid cancer and the role of oncogenic kinases.
Cell Biology Program
Cell biologist Filippo Giancotti investigates signaling by cell adhesion receptors, neoplastic transformation, and metastatic dissemination.
Developmental Biology Program
Developmental biologist Anna-Katerina Hadjantonakis studies cell lineage commitment, tissue patterning, and morphogenesis in the early mammalian embryo.
Chair, Cell Biology Program, SKI
Cell Biology Program
Cell Biology Program Chair Alan Hall studies Rho and Ras GTPases and the control of cell migration, morphogenesis, and polarity.
Cell Biology Program
Cell biologist Cole Haynes focuses on the molecular mechanisms of mitochondrial function during development, aging, and cancer cell growth.
Cancer Biology & Genetics Program
Physician-scientist Eric Holland focuses on the molecular mechanisms underlying the pathogenesis of CNS tumors and modeling of these cancers in the mouse.
Immunology Program
Immunologist Morgan Huse investigates intracellular signaling dynamics in lymphocytes.
Cell Biology Program
Cell biologist Xuejun Jiang studies programmed cell death, molecular mechanisms, and their roles in tumorigenesis.
Molecular Pharmacology & Chemistry Program
Cancer biologist Michael Kharas studies RNA regulators of self-renewal in both normal and leukemic hematopoiesis.
Memorial Hospital Research Laboratories
Physician-scientist Tari King studies the molecular genetics of high-risk breast lesions and the transition from in situ to invasive breast carcinoma.
Molecular Pharmacology & Chemistry Program
Physician-scientist Richard Kolesnick studies the role of ceramide signaling in radiation-induced vascular dysfunction and tumor regression.
Developmental Biology Program
Developmental biologist Elizabeth Lacy studies the mechanisms of gastrulation and organogenesis during mouse development.
Developmental Biology Program
Developmental biologist Eric Lai focuses on the control of developmental patterning by Notch signaling and microRNAs.
Human Oncology & Pathogenesis Program
Physician-scientist Ross Levine focuses on the investigation of genetic basis of hematopoietic malignancies.
Immunology Program
Immunologist Ming Li studies the mechanisms of T Cell homeostasis, tolerance, and immunity, and their relevance to autoimmune diseases and cancer.
Molecular Pharmacology & Chemistry Program
Biochemist Yueming Li studies function and regulation of transmembrane proteases and development of novel protease-based cancer therapies.
Cell Biology Program
Cell biologist Jidong Liu investigates the molecular mechanisms of RNA interference, function, and regulation of mammalian cytoplasmic processing bodies.
Structural Biology Program
Structural biologist Stephen Long studies the structural biology of ion channels and enzymatic membrane proteins.
Chair, Geoffrey Beene Cancer Research Center
Cancer Biology & Genetics Program
Biologist Scott Lowe investigates tumor-suppressor gene networks that control apoptosis and senescence.
Cell Biology Program
Cell biologist Paul Marks focuses on the study of agents that selectively target histone deacetylases and cause transformed cell growth arrest, terminal differentiation, apoptosis, and/or cell death.
Chair, Cancer Biology & Genetics Program, SKI
Cancer Biology & Genetics Program
Cancer Biology & Genetics Program Chair Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
Human Oncology & Pathogenesis Program
Physician-scientist Ingo Mellinghoff studies signal transduction alterations in primary brain tumors.
Immunology Program
Physician-scientist Eric Pamer studies T cell and innate inflammatory responses to bacterial and fungal infections.
Memorial Hospital Research Laboratories
Physician-scientst Ying-Xian Pan studies the transcription regulation and function of opioid receptor genes.
Molecular Pharmacology & Chemistry Program
Pharmacologist Gavril Pasternak studies molecular mechanisms of opioid receptor actions, analgesics, and G-protein-coupled receptors.
Chair, Structural Biology Program, SKI
Structural Biology Program
Structural Biology Program Chair Nikola Pavletich studies the structural biology of oncogenes and tumor suppressors.
Molecular Biology Program
Molecular biologist John Petrini investigates the repair of chromosomal breaks and the activation of the DNA-damage-induced cell-cycle checkpoints.
Molecular Biology Program
Molecular biologist Mark Ptashne studies mechanisms of gene regulation.
Cell Biology Program
Cell biologist Marilyn Resh investigates the regulation of protein function by fatty acylation, and the development of Hedgehog palmitoylation inhibitors to block pancreatic cancer.
Molecular Pharmacology & Chemistry Program
Pharmacologist Neal Rosen focuses on understanding biochemical mechanisms underlying phenotypes caused by tyrosine kinase activation in epithelial tumors and developing new therapeutic strategies.
Molecular Pharmacology & Chemistry Program
Immunologist Michel Sadelain studies the mechanisms governing transgene expression, stem cell engineering, and genetic strategies to enhance immunity against cancer.
Chair, Human Oncology and Pathogenesis Program
Human Oncology & Pathogenesis Program
Human Oncology and Pathogenesis Program Chair Charles Sawyers develops molecularly targeted cancer therapy.
Memorial Hospital Research Laboratories
Physician-scientist Gary Schwartz focuses on the identification of cell-cycle inhibitors that promote chemotherapy-induced apoptosis and their use in cancer therapy.
Memorial Hospital Research Laboratories
Physician-scientist Bhuvanesh Singh focuses on delineating the role of ubiquitination in cancer pathogenesis.
Developmental Biology Program
Developmental biologist Lorenz Studer investigates stem cells as tools to understand normal and pathological development in the CNS and to develop cell-based strategies for neural repair.
President and CEO, Memorial Sloan-Kettering Cancer Center
Cancer Biology & Genetics Program
Memorial Sloan-Kettering President Craig Thompson studies molecular signaling pathways that regulate nutrient uptake and the role these pathways play in the regulation of cell growth and survival.
Developmental Biology Program
Developmental biologist Nicholas Tolwinski studies the molecular mechanisms by which cells respond to signals and how the Wingless/Wnt pathway functions in cell behavior.
Computational Biology Program
Computational biologist Harel Weinstein investigates the structural, dynamic, and integrative determinants of molecular and cellular mechanisms underlying physiological function and pharmacological activity.
Cancer Biology & Genetics Program
Cancer biologist Hans-Guido Wendel focuses on modeling the genetics of tumor initiation, progression, and treatment response in vivo.
Immunology Program
Physician-scientist Jedd Wolchok investigates novel approaches for cancer immunotherapy and mechanisms of tumor cell–immune cell interactions.
Developmental Biology Program
Developmental biologist Jennifer Zallen focuses on the generation of tissue structure through the collective action of cell populations.
Molecular Biology Program
Molecular biologist Xiaolan Zhao studies chromosomal organization, telomere metabolism, DNA repair, and dynamic protein modification in stable genome maintenance.
