Computational Biology Program
Computational biologist Grégoire Altan-Bonnet focuses on probing and testing the integration of cellular activation that makes up the immune response.
Developmental Biology Program
Developmental biologist Mary Baylies studies the mechanisms underlying the specification and morphogenesis of muscle during development and disease.
Molecular Pharmacology & Chemistry Program
Physician-scientist Ronald Blasberg focuses on the development of noninvasive imaging paradigms in living organisms using radionuclide and optical reporter systems.
Memorial Hospital Research Laboratories
Clinician-scientist Michelle Bradbury develops translational, tumor-targeting, PET-optical silica nanoparticle probes for diagnostics, drug delivery, and sensing.
Memorial Hospital Research Laboratories
Physician-scientist Jorge Carrasquillo focuses on the development of targeted radioimmunotherapy drugs.
Cell Biology Program
Geneticist Raju Chaganti studies genomic instability in cancer cells and its implications for clinical behavior of tumors and normal cellular developmental pathways.
Cell Biology Program
Cell biologist Emily Arias Foley investigates the molecular mechanisms of mitosis.
Memorial Hospital Research Laboratories
Physician-scientist Yuman Fong develops herpes-based oncolytic viral therapies for the treatment of malignancy.
Molecular Pharmacology & Chemistry Program
Zvi Fuks studies mechanisms of radiation-induced damage and the clinical basis of radiation resistance.
Cell Biology Program
Cell biologist Filippo Giancotti investigates signaling by cell adhesion receptors, neoplastic transformation, and metastatic dissemination.
Developmental Biology Program
Developmental biologist Mary Goll investigates the mechanisms of epigenetic regulation and its role in development using zebrafish as a model system.
Molecular Pharmacology & Chemistry Program
Radiologist Jan Grimm develops novel activatable molecular imaging approaches for improved detection and monitoring of prostate and other cancers.
Developmental Biology Program
Developmental biologist Anna-Katerina Hadjantonakis studies cell lineage commitment, tissue patterning, and morphogenesis in the early mammalian embryo.
Molecular Pharmacology & Chemistry Program
Chemist Daniel Heller focuses on biomaterials and nanoscale engineering for molecular sensors and targeted therapeutics.
Cancer Biology & Genetics Program
Physician-scientist Eric Holland focuses on the molecular mechanisms underlying the pathogenesis of CNS tumors and modeling of these cancers in the mouse.
Immunology Program
Cancer immunologist Alan Houghton studies the immune response to cancer, immune recognition of self and mutated molecules, and development of new immunotherapies.
Molecular Pharmacology & Chemistry Program
Radiologist Hedvig Hricak researches methodologies of molecular imaging of prostate and gynecologic tumors.
Memorial Hospital Research Laboratories
Medical physicist John Humm focuses on noninvasive imaging of the tumor microenvironment using nuclear imaging methods.
Immunology Program
Immunologist Morgan Huse investigates intracellular signaling dynamics in lymphocytes.
Molecular Biology Program
Molecular biologist Prasad Jallepalli studies mechanisms of high-fidelity chromosome segregation in human cells.
Cancer Biology & Genetics Program
Cancer biologist Johanna Joyce investigates the signaling pathways between cancer cells and their microenvironment in tumor progression, metastasis, and response to therapy.
Developmental Biology Program
Developmental biologist Julia Kaltschmidt investigates the mechanisms of synaptic specificity underlying mammalian neuronal circuit formation.
Memorial Hospital Research Laboratories
Physician-scientist Moritz Kircher develops novel molecular imaging approaches with a focus on surface-enhanced Raman spectroscopy and magnetic resonance imaging.
Memorial Hospital Research Laboratories
Physician-scientist Jason Koutcher studies applications of magnetic resonance spectroscopy and imaging to enhance the therapeutic gain of different antineoplastic modalities.
Developmental Biology Program
Developmental biologist Elizabeth Lacy studies the mechanisms of gastrulation and organogenesis during mouse development.
Molecular Pharmacology & Chemistry Program
Radiologist Steven Larson focuses on molecular imaging in animals and humans using high-resolution diagnostic instruments, such as positron emission tomography, and single photon emission tomography.
Memorial Hospital Research Laboratories
Radiochemist Jason Lewis develops radiopharmaceuticals for the imaging and therapy of cancer.
Molecular Pharmacology & Chemistry Program
Biochemist Yueming Li studies function and regulation of transmembrane proteases and development of novel protease-based cancer therapies.
Molecular Pharmacology & Chemistry Program
Imaging specialist Clifton Ling focuses on the study and noninvasive imaging of tumor hypoxia.
Chair, Cancer Biology & Genetics Program, SKI
Cancer Biology & Genetics Program
Cancer Biology & Genetics Program Chair Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
Cell Biology Program
Cell biologist Philipp Niethammer investigates wound responses in vertebrates on a systems biology level using advanced imaging approaches and genomic techniques.
Memorial Hospital Research Laboratories
Physician-scientst Ying-Xian Pan studies the transcription regulation and function of opioid receptor genes.
Molecular Pharmacology & Chemistry Program
Pharmacologist Gavril Pasternak studies molecular mechanisms of opioid receptor actions, analgesics, and G-protein-coupled receptors.
Structural Biology Program
Structural biologist Alexandros Pertsinidis uses structural molecular and structural cell biology to study novel optical imaging and spectroscopy technologies to understand the function of complex macromolecular machines inside living cells.
Molecular Biology Program
Molecular biologist John Petrini investigates the repair of chromosomal breaks and the activation of the DNA-damage-induced cell-cycle checkpoints.
Memorial Hospital Research Laboratories
Physician-scientist Vladimir Ponomarev focuses on developing reporter genetic systems for specific applications such as sequential in vivo imaging studies in cancer biology, cancer immunotherapy, and radiation sciences.
Molecular Biology Program
Molecular biologist Xiaohui Qu conducts high-resolution, single-molecule studies of the molecular mechanisms of ribosome functions and gene expression control.
Memorial Hospital Research Laboratories
Optical engineer Milind Rajadhyaksha studies confocal microscopy for the imaging of cancer, technology development, and translational and clinical studies in skin and head and neck cancers.
Cell Biology Program
Cell biologist Marilyn Resh investigates the regulation of protein function by fatty acylation, and the development of Hedgehog palmitoylation inhibitors to block pancreatic cancer.
Molecular Pharmacology & Chemistry Program
Immunologist Michel Sadelain studies the mechanisms governing transgene expression, stem cell engineering, and genetic strategies to enhance immunity against cancer.
Chair, Molecular Pharmacology & Chemistry Program, SKI
Molecular Pharmacology & Chemistry Program
Molecular Pharmacology and Chemistry Program Chair David Scheinberg focuses on the discovery and development of novel, specific immunotherapeutic agents and targeted nanodevices for cancer therapy.
Memorial Hospital Research Laboratories
Physician-scientist Samuel Singer studies the genomic alterations that define new targets for therapy in sarcoma.
Immunology Program
Physician-scientist Marcel R. M. van den Brink studies the immunology of bone marrow transplantation.
Developmental Biology Program
Developmental biologist Jennifer Zallen focuses on the generation of tissue structure through the collective action of cell populations.
Memorial Hospital Research Laboratories
Medical physicist Pat Zanzonico fosuses on radionuclide-based methods for detecting and localizing tumor hypoxia, immune effector-cell trafficking, patient-specific dosimetry for radionuclide therapies, and small-animal and molecular imaging.
Molecular Biology Program
Molecular biologist Xiaolan Zhao studies chromosomal organization, telomere metabolism, DNA repair, and dynamic protein modification in stable genome maintenance.
