Find Faculty & Laboratory Staff

A

Antonescu, Cristina R.
Memorial Hospital Research Laboratories
Physician-scientist Cristina Antonescu studies the molecular pathogenesis of soft tissue sarcomas and gastrointestinal stromal tumors.

B

Bao, Zhirong
Developmental Biology Program
Developmental biologist Zhirong Bao investigates how the genome dictates development using C. elegans as a model.
Pictured Mary Baylies
Baylies, Mary
Developmental Biology Program
Developmental biologist Mary Baylies studies the mechanisms underlying the specification and morphogenesis of muscle during development and disease.
Pictured: Robert Benezra
Benezra, Robert
Cancer Biology & Genetics Program
Cancer biologist Robert Benezra studies the molecular mechanisms of tumor growth and progression using mouse Id1 and Id3 knockout models and analysis of the spindle assembly checkpoint.
Pictured: Peter Besmer
Besmer, Peter
Developmental Biology Program
Developmental biologist Peter Besmer focuses on normal and oncogenic receptor tyrosine kinase signaling in vitro and in vivo in mice.
Pictured: Ronald Blasberg
Blasberg, Ronald G.
Molecular Pharmacology & Chemistry Program
Physician-scientist Ronald Blasberg focuses on the development of noninvasive imaging paradigms in living organisms using radionuclide and optical reporter systems.
Brennan, Cameron W.
Human Oncology & Pathogenesis Program
Physician-scientist Cameron Brennan focuses on genomic analysis of human and mouse gliomas and medulloblastomas.
Bromberg, Jacqueline
Memorial Hospital Research Laboratories
Physician-scientist Jacqueline Bromberg focuses on aberrantly activated Stat3 and the mechanisms of Stat3-mediated transformation.

C

Pictured: Brett S. Carver
Carver, Brett S.
Memorial Hospital Research Laboratories
Physician-scientist Brett Carver focuses on the identification of molecular pathways involved in prostate cancer initiation and progression.
Pictured: Raju Chaganti
Chaganti, Raju
Cell Biology Program
Geneticist Raju Chaganti studies genomic instability in cancer cells and its implications for clinical behavior of tumors and normal cellular developmental pathways.
Pictured: Timothy Chan
Chan, Timothy A.
Human Oncology & Pathogenesis Program
Physician-scientist Timothy Chan focuses on the identification and characterization of tumor suppressors in glioblastoma and breast cancer.
Pictured: Yu Chen
Chen, Yu
Human Oncology & Pathogenesis Program
Physician-scientist Yu Chen studies the role of transcription factors that are critical for prostate cancer development.

F

Pictured: James Fagin
Fagin, James A.
Human Oncology & Pathogenesis Program
Physician-scientist James Fagin focuses on the pathogenesis of thyroid cancer and the role of oncogenic kinases.
Pictured: Zvi Fuks
Fuks, Zvi
Molecular Pharmacology & Chemistry Program
Zvi Fuks studies mechanisms of radiation-induced damage and the clinical basis of radiation resistance.

G

Giancotti, Filippo
Cell Biology Program
Cell biologist Filippo Giancotti investigates signaling by cell adhesion receptors, neoplastic transformation, and metastatic dissemination.
Pictured: Jan Grimm
Grimm, Jan
Molecular Pharmacology & Chemistry Program
Radiologist Jan Grimm develops novel activatable molecular imaging approaches for improved detection and monitoring of prostate and other cancers.

H

Pictured: Alan Hall
Hall, Alan
Chair, Cell Biology Program, SKI
Cell Biology Program
Cell Biology Program Chair Alan Hall studies Rho and Ras GTPases and the control of cell migration, morphogenesis, and polarity.
Haynes, Cole
Cell Biology Program
Cell biologist Cole Haynes focuses on the molecular mechanisms of mitochondrial function during development, aging, and cancer cell growth.
Pictured: Alan Houghton
Houghton, Alan
Immunology Program
Cancer immunologist Alan Houghton studies the immune response to cancer, immune recognition of self and mutated molecules, and development of new immunotherapies.
Pictured: James J. Hsieh
Hsieh, James J.
Human Oncology & Pathogenesis Program
Physician-scientist James Hsieh focuses on developing novel therapeutics targeting cancer cell proliferation; he also directs Memorial Sloan Kettering’s translational kidney cancer research program.
Pictured: Jason T. Huse
Huse, Jason T.
Human Oncology & Pathogenesis Program
Physician-scientist Jason Huse focuses on the molecular pathogenesis of brain tumors, particularly high-grade gliomas.

I

Pictured: Christine Iacobuzio-Donahue
Iacobuzio-Donahue, Christine A.
Associate Director for Translational Research, David M. Rubenstein Center for Pancreatic Cancer Research
Human Oncology & Pathogenesis Program
Physician-scientist Christine Iacobuzio-Donahue studies the genomics and cell biology of pancreatic and other solid tumors as it relates to subclonal evolution, tumor progression, and metastasis.

J

Pictured: Maria Jasin
Jasin, Maria
Developmental Biology Program
Developmental biologist Maria Jasin focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
Pictured: Johanna Joyce
Joyce, Johanna
Cancer Biology & Genetics Program
Cancer biologist Johanna Joyce investigates the signaling pathways between cancer cells and their microenvironment in tumor progression, metastasis, and response to therapy.

K

Pictured: Tari King
King, Tari A.
Memorial Hospital Research Laboratories
Physician-scientist Tari King studies the molecular genetics of high-risk breast lesions and the transition from in situ to invasive breast carcinoma.
Pictured: Moritz Kircher
Kircher, Moritz F.
Memorial Hospital Research Laboratories
Physician-scientist Moritz Kircher develops novel molecular imaging approaches with a focus on surface-enhanced Raman spectroscopy and magnetic resonance imaging.
Koff, Andrew
Molecular Biology Program
Molecular biologist Andrew Koff investigates the role of cell cycle inhibitors in differentiation and how their loss affects tumorigenesis.
Pictured: Richard Kolesnick
Kolesnick, Richard N.
Molecular Pharmacology & Chemistry Program
Physician-scientist Richard Kolesnick studies the role of ceramide signaling in radiation-induced vascular dysfunction and tumor regression.
Koutcher, Jason A.
Memorial Hospital Research Laboratories
Physician-scientist Jason Koutcher studies applications of magnetic resonance spectroscopy and imaging to enhance the therapeutic gain of different antineoplastic modalities.

L

Pictured: Marc Ladanyi
Ladanyi, Marc
Human Oncology & Pathogenesis Program
Molecular pathologist Marc Ladanyi studies the molecular pathogenesis of sarcomas, lung cancer, and mesothelioma.
Larson, Steven M.
Molecular Pharmacology & Chemistry Program
Radiologist Steven Larson focuses on molecular imaging in animals and humans using high-resolution diagnostic instruments, such as positron emission tomography, and single photon emission tomography.
Li, Ming
Immunology Program
Immunologist Ming Li studies mechanisms of immune regulation, and their relevance to diseases including cancer.
Pictured: Yueming Li
Li, Yueming
Molecular Pharmacology & Chemistry Program
Biochemist Yueming Li studies function and regulation of transmembrane proteases and development of novel protease-based cancer therapies.
Pictured: Scott Lowe
Lowe, Scott W.
Chair, Cancer Biology & Genetics Program, SKI; Chair, Geoffrey Beene Cancer Research Center
Cancer Biology & Genetics Program
Biologist Scott Lowe investigates tumor-suppressor gene networks that control apoptosis and senescence.
Luo, Minkui
Molecular Pharmacology & Chemistry Program
Chemist Minkui Luo develops and implements the combined chemical and biological tools to define and manipulate epigenetic functions of protein methyltransferases for disease diagnosis and therapy.

M

Pictured: Joan Massagué
Massagué, Joan
Director, Sloan Kettering Institute
Cancer Biology & Genetics Program
Sloan Kettering Institute Director Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
Pictured: Christine Mayr
Mayr, Christine
Cancer Biology & Genetics Program
Cancer biologist Christine Mayr focuses on gene regulation and definition of the end of an mRNA or a transcription unit.
Pictured: Ingo Mellinghoff
Mellinghoff, Ingo K.
Human Oncology & Pathogenesis Program
Physician-scientist Ingo Mellinghoff studies signal transduction alterations in primary brain tumors.
Pictured: Malcolm Moore
Moore, Malcolm A. S.
Cell Biology Program
Cell biologist Malcolm Moore focuses on the characterization of normal and cancer stem cells and the development of selective therapies.

O

Pictured: Michael Overholtzer
Overholtzer, Michael
Cell Biology Program
Cell biologist Michael Overholtzer studies the mechanisms of tumor initiation and progression, cell adhesion, and cell death.

P

Petrini, John
Molecular Biology Program
Molecular biologist John Petrini investigates the repair of chromosomal breaks and the activation of the DNA-damage-induced cell-cycle checkpoints.

R

Pictured: Shyam Rao
Rao, Shyam S.
Memorial Hospital Research Laboratories
Physician-scientist Shyam Rao studies the role of the tumor microenvironment in tumorigenesis and response to radiation therapy.
Pictured: Jorge S. Reis-Filho
Reis-Filho, Jorge S.
Human Oncology & Pathogenesis Program
Physician-scientist Jorge Reis-Filho focuses on the development of a predictive molecular classification for rare types of breast cancer and characterization of intratumor genetic heterogeneity in breast cancers.
Pictured: Neal Rosen
Rosen, Neal
Molecular Pharmacology & Chemistry Program
Pharmacologist Neal Rosen focuses on understanding biochemical mechanisms underlying phenotypes caused by tyrosine kinase activation in epithelial tumors and developing new therapeutic strategies.
Pictured: Charles Rudin
Rudin, Charles M.
Memorial Hospital Research Laboratories
Physician-scientist Charles Rudin focuses on the development and testing of novel therapeutic approaches to lung cancer in preclinical models.

S

Sawyers, Charles L.
Chair, Human Oncology and Pathogenesis Program
Human Oncology & Pathogenesis Program
Human Oncology and Pathogenesis Program Chair Charles Sawyers develops molecularly targeted cancer therapy.
Scheinberg, David A.
Chair, Molecular Pharmacology & Chemistry Program, SKI
Molecular Pharmacology & Chemistry Program
Molecular Pharmacology and Chemistry Program Chair David Scheinberg focuses on the discovery and development of novel, specific immunotherapeutic agents and targeted nanodevices for cancer therapy.
Pictured: Samuel Singer
Singer, Samuel
Memorial Hospital Research Laboratories
Physician-scientist Samuel Singer studies the genomic alterations that define new targets for therapy in sarcoma.
Pictured: David Solit
Solit, David B.
Director, Marie-Josée & Henry R. Kravis Center for Molecular Oncology
Human Oncology & Pathogenesis Program
Physician-scientist David Solit studies human oncology and pathogenesis, genomics, oncogenes and tumor suppressors, cancer therapeutics, and clinical trials.
Pictured: David Spriggs
Spriggs, David R.
Memorial Hospital Research Laboratories
Physician-scientist David Spriggs studies the molecular mechanisms of drug resistance in ovarian cancer.

T

Pictured: Viviane Tabar
Tabar, Viviane
Memorial Hospital Research Laboratories
Physician-scientist Viviane Tabar focuses on in vivo applications of neural derivatives of pluripotent stem cells (such as iPS and ES cells) and on cancer stem cells in human brain tumors.
Pictured: Laura H. Tang
Tang, Laura H.
Memorial Hospital Research Laboratories
Physician-scientist Laura Tang studies the molecular pathogenesis of cell transformation in neuroendocrine neoplasms of the gastrointestinal tract and pancreas and adenocarcinomas of the stomach and gastrointestinal junction.
Sunitha B. Thakur, PhD
Thakur, Sunitha B.
Memorial Hospital Research Laboratories
Medical physicist Sunitha Thakur focuses on MR biomarkers for early detection and monitoring response to treatment.

V

Pictured: Andrea Ventura
Ventura, Andrea
Cancer Biology & Genetics Program
Cancer biologist Andrea Ventura studies non-coding RNAs in cancer and development

W

Pictured: Martin R. Weiser
Weiser, Martin R.
Memorial Hospital Research Laboratories
Physician-scientist Martin Weiser investigates the mechanisms underlying tumor spread and metastasis and how these mechanisms could be targeted.
Pictured: Hans-Guido Wendel
Wendel, Hans-Guido
Associate Member
Cancer Biology & Genetics Program
Cancer biologist Hans-Guido Wendel focuses on modeling the genetics of tumor initiation, progression, and treatment response in vivo.
Pictured: Richard White
White, Richard Mark
Cancer Biology & Genetics Program
Cancer biologist Richard Mark White investigates the evolution of metastases in zebrafish.

Y

Pictured: Sam Yoon
Yoon, Sam S.
Memorial Hospital Research Laboratories
Physician-scientist Sam Yoon studies the role of tumor microenvironment in the progression and radiation response of sarcomas and gastric cancer.

Z

Pictured: Jennifer Zallen
Zallen, Jennifer A.
Developmental Biology Program
Developmental biologist Jennifer Zallen focuses on the generation of tissue structure through the collective action of cell populations.
Pictured: Pat Zanzonico
Zanzonico, Pat B.
Memorial Hospital Research Laboratories
Medical physicist Pat Zanzonico focuses on radionuclide-based methods for detecting and localizing tumor hypoxia, immune effector-cell trafficking, patient-specific dosimetry for radionuclide therapies, and small-animal and molecular imaging.