Postdoctoral Fellow with
Prof. James S. Panek
Department of Chemistry
Boston University

PhD, Cornell University, 2007

Tri-Institutional Training Program in Chemical Biology

BS, Case Western Reserve University, 2001

Frank L. Horsfall, Jr. Fellow, 2006–2007

Thesis: Synthesis of a Structurally and Stereochemically Diverse Spiroketal Library Using Novel Stereoselective Spirocyclizations of C1-Substituted Glycal Epoxides, May 14, 2007

5) Moilanen, S. B.; Potuzak, J. S.; Tan, D. S.* “Stereocontrolled synthesis of spiroketals via Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration.” J. Am. Chem. Soc. 2006, 128, 1792-1793.

[ Abstract | PDF | Supporting Info | PMC ]
• Highlighted in Nature
4) Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* “Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction.” J. Am. Chem. Soc. 2005, 127, 13796-13797.

[ Abstract | PDF | Supporting Info ]
3) Moilanen, S. B.; Tan, D. S.* “Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: New insights into glycal reactivity.” Org. Biomol. Chem. 2005, 3, 798-803.

[ Abstract | PDF | Supporting Info ]
2) Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* “Discovery and applications of small molecule probes for studying biological processes.” Biotechnol. Genet. Eng. Rev. 2004, 21, 11-78.

[ Journal ]
1) Garner, P.*; Sherry, B.; Moilanen, S.; Huang, Y. “In vitro stability of α-helical peptide nucleic acids (αPNAs).” Bioorg. Med. Chem. Lett. 2001, 11, 2315-2317.

[ Abstract | PDF ]
09/01/2006 27th Annual Convocation Ceremony (MSKCC Center News)

Sirkka Moilanen was awarded a Frank L. Horsfall, Jr. Fellowship for 2006-2007. [Full text]
02/02/2006 Chemistry: Order of the rings (Nature)

One of the great challenges in organic chemistry is developing novel ways to synthesize complex structures. The best reactions work for a range of chemical substrates, and give high yields. By these criteria, a reaction, discovered by Derek Tan of the Memorial Sloan-Kettering Cancer Center in New York and his co-workers is near ideal. [Full text]
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