The research in our laboratory is aimed at structural characterization of the molecular mechanisms of cell-cell interactions and signal transduction in the nervous system. We are particularly interested in understanding the processes of generating correct neuronal connectivity in the developing mammalian CNS. We use x-ray crystallography combined with other biophysical and biochemical techniques to study axon guidance molecules and their interactions with neuronal cell-surface receptors.

Office phone:
Laboratory phone:
212-639-6837 / 6806
Laboratory fax: