Stem Cell Research Facility -- Core Facility

Mark Tomishima (Core Facility Head)
Office phone:
212-639-3913
Office fax:
646-422-2062
E-mail(s)
tomishim@mskcc.org

Human mesenchymal progenitors derived from H9 hES cells. Vimentin immunoreactivity (red) and nuclei (blue) are overlaid on a transmitted light image. Enlarge Image Human mesenchymal progenitors derived from H9 hES cells. Vimentin immunoreactivity (red) and nuclei (blue) are overlaid on a transmitted light image.

The SKI Stem Cell Research Facility expands, characterizes and distributes non-NIH approved human embryonic stem (hES) cells isolated at the Weill-Cornell and Rockefeller University derivation core facilities. We are a part of the Starr Foundation-funded Tri-Institutional Stem Cell Initiative that is developing shared stem cell expertise and resources between Memorial Sloan Kettering, Weill-Cornell, and Rockefeller University. In addition to characterizing new Tri- Institutional hES lines, we will provide :

  • Training in hES cell culture
     
  • Transgenic hES cells and services
     
  • Neural or mesenchymal progenitors derived from mouse or human ES cells

Additionally, we are refining new technologies in hES culture. Homologous recombination and BAC transgenesis are currently being developed, and we hope to offer these techniques as services in the future. We are also investigating new culture conditions that might enhance the long-term maintenance of human ES cells in culture.