Current Research:

Dr. Gönen's clinical collaborations focus on surgical treatment of gastrointestinal and hepatobiliary cancers, including staging and prognostication. He also has a long-standing collaboration with Nuclear Medicine which encompasses the development of Positron Emission Tomography (PET) in cancer diagnosis and prognosis. Most of Dr Gönen's methodological research originates from these collaborations, including building, assessing and comparing predictive models as well as the design and analysis of clinical trials with imaging endpoints. He recently published a book on the use of receiver operating characteristic (ROC) curves using SAS®.

Dr. Gönen is the director of the Clinical Trials Design Workshop and he serves on the faculty and program committee of AACR/ASCO Vail Workshop on Method in Clinical Cancer Research. He is the chair of the committee on international relations of the American Statistical Association. He is currently serving on the editorial boards of Clinical Trials: Journal of the Society of Clinical Trials and Gastrointestinal Cancer Research.

Selected Bibliography:

1. Gönen M, Westfall PH, Johnson WO. Bayesian multiple testing for two-sample multivariate endpoints. Biometrics. 2003;59:76-82.

2. Gönen M, Johnson WO, Lu Y, Westfall PH. A Bayesian two-sample t-test. The American Statistician 2005;59:252-257.

3. Gönen M, Heller G. Concordance Probability and Discriminative Power of Proportional Hazards Regression. Biometrika 2005;92:965-970.

4. Gönen M, Schrag D, Weiser M. Nodal Staging Score: A Tool to Assess Adequate Staging of Node-Negative Colon Cancer. Journal of Clinical Oncology, 2009, in press.

5. Gönen M, Heller G. Lehmann Family of ROC Curves. Medical Decision Making, 2009, in press.