Current Research Interests:

Dr. Begg is interested in cancer epidemiology, health services research, and the statistical methods that support these and other research projects.  He has been pursuing the idea that cancer risk can be determined by studying patients with multiple primary malignancies. His recent work has been focused on cancer risk prediction in carriers of major cancer genes. He is also investigating statistical methods for distinguishing second cancers from metastases using genetic profiling of the tumors.

Selected Bibliography:

1. Begg CB. The search for cancer risk factors: when can we stop looking? (with commentaries) Am J Public Health 2001;91:360-364.

2. Begg CB, Riedel ER, Bach PB, Kattan MW, Schrag D, Warren JL, Scardino PT. Variations in morbidity following radical prostatectomy (with editorial). New Engl J Med 2002; 346:1138-1144.

3. Begg CB. On the use of familial aggregation in population-based case probands for calculating penetrance (with editorial). J Natl Cancer Inst 2002;94:1221-1226.

4. Begg CB, Haile RW, Borg A, Malone KE, Concannon P, Thomas DC, Langholz B, Bernstein L,Olsen JH, Lynch CF, Anton-Culver H, Capanu M, Liang X, Hummer AJ, Sima C, Bernstein JL. Variation of breast cancer risk among BRCA1/2 carriers. JAMA 2008; 299(2):194-201.

5. Begg CB, Hummer AJ, Mujumdar U, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber SB, Culver HA, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Klaus Busam, From L, Berwick M. A design for cancer case-control studies using only incident cases: experience with the GEM study of melanoma. Int. J. Epidemiol; 2006; 35: 756-764.