Mithat Gönen, PhD

Chief, Biostatistics Service
Pictured: Mithat Gönen
Office Phone:
Texas Tech University

Dr. Gönen's translational and clinical collaborations focus on genomic profiling of hematologic malignancies, surgical treatment of gastrointestinal and hepatobiliary cancers and development and evaluation of novel molecular imaging technologies. Most of Dr Gönen's methodological research originates from these collaborations, including building, assessing and comparing prognostic and predictive models; design and analysis of clinical trials and imaging studies; as well as Bayesian methods. He is the principal investigator of a 2012 Geoffrey Beene Grant Award on Integrated Genetic Profiling to Predict Response to Therapy in Acute Myeloid Leukemia. He is the author of a book on the use of receiver operating characteristic (ROC) curves using SAS®

Dr. Gönen was a co-director of the AACR/ASCO Vail Workshop on Methods in Clinical Cancer Research from 2011 to 2013 and a member of ASCO's Cancer Research Committee from 2012 to 2014. He has been serving the Society for Clinical Trials in various roles: Program Chair for the 2012 Annual Meeting, deputy editor of Clinical Trials: Journal of the Society for Clinical Trials and member of the board of directors. Dr. Gönen is a fellow the American Statistical Association and is an associate editor of Statistics in Biopharmaceutical Research, an ASA journal. He will serve as the Program Chair for ENAR's 2015 Spring Meeting.

Publications by Mithat Gönen

Gönen M. Optimal Bayesian Enrichment: A View from the Closet. Biometrics (invited discussion). 2011, Early view (June 2011).

Haeno H*, Gönen M*, Davis MB, Herman JM, Iacobuzio-Donahue CA, Michor F. Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies. Cell. 2012, 148:362-75 (*: equal contribution)

Patil JP*, Gönen M*, Figueora ME, Fernandez H et al. Prognostic and Therapeutic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia. New England Journal of Medicine, 2012 (*: equal contribution)

Gönen M. Visualizing Longitudinal Data with Dropouts. The American Statistician, May 2013.

Gönen M. Mixtures of Receiver Operating Characteristic Curves. Academic Radiology, August 2013 (Metz Memorial Issue).