Zhigang Zhang - Staff Member | Memorial Sloan-Kettering Cancer Center

Office Phone:

646-735-8149

E-mail:

zhangz@mskcc.org

Education:

University of Missouri-Columbia

Current Research Interests

Dr. Zhang's current research interests are survival analysis, longitudinal data analysis and semiparametric inferences. In particular, he is interested in developing methodology for data subject to complicated censorship and/or truncation, which frequently arise in clinical trials and medical studies. He is also interested in statistical research aiming at understanding the biological mechanisms of gene regulation. Dr. Zhang collaborates with colleagues in the Department of Radiation Oncology, the Department of Medical Physics and the Lymphoma Research Group.

Publications by Zhigang Zhang

Selected Publications

Z. Zhang, L. Sun, J. Sun and D. M. Finkelstein (2007). Regression analysis of failure time data with informative interval censoring. Statistics in Medicine 26, 2533-2546.

L. Sun and Z. Zhang (2009). A class of transformed mean residual life models with censored survival data. Journal of the American Statistical Association 104, 803-815.

Z. Zhang (2009). Linear transformation models for interval-censored data: prediction of survival probability and model checking. Statistical Modeling 9, 321-343.

Z. Zhang and J. Sun (2010). Interval censoring. Statistical Methods in Medical Research. To appear.

Z. Zhang, X. Zhao and L. Sun (2010). Goodness-of-fit tests for additive mean residual life model under right censoring. Lifetime Data Analysis. To appear.

Full List of Publications

Z. Zhang, L. Sun, X. Zhao and J. Sun (2005). Regression analysis of interval censored failure time data with linear transformation models. Canadian Journal of Statistics 33, 61-70.
Z. Zhang, J. Sun and L. Sun (2005). Statistical analysis of current status data with informative observation times. Statistics in Medicine 24, 1399-1407.
Z. Zhang (2006). Survival Analysis. Encyclopedia of Measurement and Statistics. Editor: Neil J. Salkind. Sage Publications.
L. Sun, Z. Zhang and J. Sun (2006). Additive hazards regression of failure time data with covariate measurement errors. Statistica Neerlandica 60, 497-509.
Z. Zhang, L. Sun, J. Sun and D. M. Finkelstein (2007). Regression analysis of failure time data with informative interval censoring. Statistics in Medicine 26, 2533-2546.
M. J. Zelefsky, Y. Yamada, Z. Fuks, Z. Zhang, M. Hunt, O. Cahlon, J. Park and A. Shippy (2008). Long-term results of conformal radiotherapy for prostate cancer: impact of dose escalation on biochemical tumor control and distant metastases-free survival outcomes. International Journal of Radiation Oncology _ Biology _ Physics 71, 1028-1033.
J. Zhang, X. Yang, Z. Yin, Z. Zhang, Z. Fuks and R. Kolesnick (2008). Downregulation of KSR1 in pancreatic cancer xenografts by antisense oligonucleotides correlates with tumor drug uptake. Cancer Biology and Therapy 7, 1490-1495.
L. Sun and Z. Zhang (2009). A class of transformed mean residual life models with censored survival data. Journal of the American Statistical Association 104, 803-815.
Z. Zhang (2009). Linear transformation models for interval-censored data: prediction of survival probability and model checking. Statistical Modeling 9, 321-343.
B. S. Hoppe, C. H. Moskowitz, Z. Zhang, J. C. Maragulia, R. D. Rice, A. S. Reiner, P. A. Hamlin, A. D. Zelenetz and J. Yahalom (2009). The role of FDGPET imaging and involved field radiotherapy in relapsed or refractory diffuse large B-cell lymphoma. Bone Marrow Transplantation 43, 941-948.
A. Rimner, M. F. Brennan, Z. Zhang, S. Singer and K. M. Alektiar (2009). Influence of compartmental involvement on the patterns of morbidity in soft tissue sarcoma of the thigh. Cancer 115, 149-157.
A. J. Moskowitz, M.-A. Perales, T. Kewalramani, J. Yahalom, H. Castro-Malaspina, Z. Zhang, J. Vanak, A. D. Zelenetz and C. H. Moskowitz (2009). Outcomes for patients who fail high dose chemoradiotherapy and autologous stem cell rescue for relapsed and primary refractory hodgkin lymphoma. British Journal of Haematology 146, 158-163.
J. Gerecitano, C. Portlock, C. Moskowitz, P. Hamlin, D. Straus, A. D. Zelenetz, Z. Zhang, O. Dumitrescu, D. Sarasohn, D. Lin, J. Pappanicholaou, B. M. Cortelli, E. Neylon, R. Hamelers, J. Wright and O. A. O'Connor (2009). Phase 2 study of weekly bortezomib in mantle cell and follicular lymphoma. British Journal of Haematology 146, 652-655.
Z. Zhang and J. Sun (2010). Interval censoring. Statistical Methods in Medical Research 19, 53-70.
Z. Zhang, X. Zhao and L. Sun (2010). Goodness-of-fit tests for additive mean residual life model under right censoring. Lifetime Data Analysis 16, 385-408.
Z. Zhang and Q. Mo (2010). Biased Estimator. Encyclopedia of Research Design. Editor: Neil J. Salkind. Sage Publications.
S. M. Edwards-Bennett, L. M. Jacks, C. H. Moskowitz, E. J. Wu, Z. Zhang, A. Noy, C. S. Portlock, D. J. Straus, A. D. Zelenetz and J. Yahalom (2010). Stanford V program for locally extensive and advanced hodgkin lymphoma: the Memorial Sloan-Kettering cancer center experience. Annals of Oncology 21, 574-581.
C. H. Moskowitz, J. Yahalom, A. D. Zelenetz, Z. Zhang, D. Filippa, J. Teruya-Feldstein, T. Kewalramani, R. D. Rice, J. Maragulia, J. Vanak, P. Hamlin, S. Horowitz, A. Noy, O. O'Connor, C. Portlock, D. Straus and S. D. Nimer (2010). High-dose chemo-radiotherapy for relapsed or refractory hodgkin lymphoma and the significance of pre-transplant functional imaging. British Journal of Haematology 148, 890-897.
D. M. Lovelock, Z. Zhang, A. Jackson, J. Keam, J. Bekelman, M. Bilsky, E. Lis and Y. Yamada (2010). Correlation of local failure with measures of dose insufficiency in the high-dose single-fraction treatment of bony metastases. International Journal of Radiation Oncology _ Biology _ Physics 77, 1282-1287.
M. J. Zelefsky, J. A. Eastham, A. M. Cronin, Z. Fuks, Z. Zhang, Y. Yamada, A. Vickers and P. T. Scardino (2010). Metastasis after radical prostatectomy orexternal beam radiotherapy for patients with clinically localized prostate cancer: a comparison of clinical cohorts adjusted for case mix. Journal of Clinical Oncology 28, 1508-1513.
H. D. Moulding, E. Lis, D. M. Lovelock, Z. Zhang, Y. Yamada, and M. H. Bilsky (2010). Local disease control after decompressive surgery and adjuvant high dose single fraction radiosurgery for spine metastases. Journal of Neurosurgery _ Spine 13, 87-93.
K. A. Goodman, E. A. Wiegner, K. E. Maturen, Z. Zhang, Q. Mo, G. Yang, I. C. Gibbs, G. A. Fisher and A. C. Koong (2010). Dose escalation study of single fraction stereotactic body radiotherapy for liver malignancies. International Journal of Radiation Oncology _ Biology _ Physics 78, 486-493.
I. Deutsch, M. J. Zelefsky, Z. Zhang, Q. Mo, M. Zaider, G. Cohen, O. Cahlon, Y. Yamada (2010). Comparison of PSA-relapse-free survival in patients treated with ultra-high dose IMRT versus combination HDR brachytherapy and IMRT. Brachytherapy 9, 313-318.
M. H. Fuchsjager, D. Pucar, M. J. Zelefsky, Z. Zhang, Q. Mo, L. S. BenPorat, A. Shukla-Dave, L.Wang, V. E. Reuter and H. Hricak (2010). Predicting post-external beam radiation therapy PSA relapse of prostate cancer using pre-treatment MRI. International Journal of Radiation Oncology _ Biology _ Physics 78, 743-50.
M. A. Kollmeier, M. S. Katz, K. Mak, Y. Yamada, D. J. Feder, Z. Zhang, X. Jia, W. Shi and M. J. Zelefsky (2011). Improved biochemical outcomes with statin use in patients with high-risk localized prostate cancer treated with radiation therapy. International Journal of Radiation Oncology _ Biology _ Physics 79, 713-718..
Z. A. Alicikus, Y. Yamada, Z. Zhang, X. Pei, M. Hunt, M. Kollmeier, B. Cox and M. J. Zelefsky (2011). Ten-year outcomes of high-dose intensity-modulated radiotherapy for localized prostate cancer. Cancer 117, 1429-1437.
C. A. Barker, R. Mutter and Z. Zhang(2011). Contrast media use in radiation oncology: a prospective, controlled educational intervention study with retrospective analysis of patient outcomes. Journal of the American College of Radiology 7, 967-974.
M. J. Zelefsky, M. Worman, G. N. Cohen, X. Pei, M. Kollmeier, Y. Yamada, B. Cox, Z. Zhang, E. Bieniek, L. Dauer and M. Zaider (2011). Real-time intraoperative computed tomography assessment of quality of permanent interstitial seed implantation for prostate cancer. Urology 76, 1138-1142.
M. J. Zelefsky, Y. Yamada, X. Pei, M. Hunt, G. Cohen, Z. Zhang, M. Zaider (2011). Comparison of tumor control and toxicity outcomes of high dose intensity modulated radiotherapy and brachytherapy for patients with favorable risk prostate cancer. Urology 77, 986-990.
J. Gerecitano, C. Portlock, P. Hamlin, C. H. Moskowitz, A. Noy, D. Straus, P. Schulman, A. Iasonos, Z. Zhang, Q. Mo, etc. (2011). Phase I trial of weekly and twice-weekly bortezomib with rituximab, cyclophosphamide, and prednisone in relapsed or refractory non-Hodgkin lymphoma. Clinical Cancer Research 17, 2493-2501.

About Our Research

Research Programs & Departments

Research Resources

Pre- and Postdoctoral Training

Career Opportunities

Zhigang Zhang, PhD

Current Research Interests

Selected Publications

About Our Research

Research Programs & Departments

Research Resources

Pre- and Postdoctoral Training

Career Opportunities

About Memorial
Sloan-Kettering

Zhigang Zhang, PhD

Current Research Interests

Selected Publications

My Seminars

About MemorialSloan-Kettering

About Memorial
Sloan-Kettering