Human Oncology & Pathogenesis Program

Our teams of physician-scientists are working to translate molecular insights into new treatments for cancer.

Physician-scientist David Solit focuses on the development of cancer therapies that target pathways responsible for cancer initiation and progression.

James A. Fagin »

Physician-scientist James Fagin focuses on the pathogenesis of thyroid cancer and the role of oncogenic kinases.

Ping Chi »

Physician-scientist Ping Chi studies genetic and epigenetic mechanisms of transcriptional regulation by oncogenic transcription factors in GIST and other solid tumors.

Sarat Chandarlapaty »

Physician-scientist Sarat Chandarlapaty studies the regulation of growth factor signaling networks in cancer.

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In this section

HOPP Year in Review

One of the goals of the Human Oncology and Pathogenesis Program (HOPP) is to achieve progress in various areas of cancer research. In our 2011 Year in Review, learn about our collaborations, innovations, and training that have had an impact on Memorial Sloan-Kettering and its patients.

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Charles Sawyers Discusses New Report about Cancer Progress and Challenges

Memorial Sloan-Kettering physician-scientist Charles Sawyers, who serves as president of the American Association for Cancer Research, highlights findings from the group’s new report.

Investigators Sequence the Genome of a Rare Head and Neck Cancer

Investigators have sequenced the genome of adenoid cystic carcinoma, a rare and deadly head and neck cancer. The work sets the stage for the sequencing of additional rare cancers at Memorial Sloan-Kettering.

Pictured: Timothy Chan

A Look Inside the Geoffrey Beene Cancer Research Center

Watch our scientists discuss how the Geoffrey Beene Center helped Memorial Sloan-Kettering establish a progressive approach to modern cancer research.

Pictured: Scott Lowe & Zhen Zhao