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Cortical neurons derived from human pluripotent stem cells
In the Lab
A 'Quick-and-Easy' Recipe for Making Brain Cells

Using stem cells, scientists can create batches of cortical neurons to study schizophrenia and autism.
Illustration of DNA with green wrench making adjustments to a nut on the double helix.
Science Byte
A Clean Break: Scientists Make Surprising Discoveries about DNA Repair

A study reveals unexpected insights into how cells prepare broken DNA strands to be rejoined, preventing mutations that can cause cancer.
PET/CT scan of mouse prostate (displayed in green and orange).
In the Lab
More Precise Imaging of Prostate Cancer Could Give Insight into Drug Effectiveness

An antibody that targets a protein specific to prostate cells can be used to image prostate cancer more clearly and indicate how well drugs are working.
T cells on the loose.
Feature
T Is for T Cell: The Science Behind Immunotherapy

By deciphering the biology of T cells, MSK scientists gave immunotherapy a boost.
Image of fireball-type explosion on black background.
In the Lab
Researchers Gain Insight into How a Drug Fires Up an Immune Response to Cancer

Scientists have learned that a drug activates a form of highly inflammatory programmed cell death called pyroptosis — a discovery that sheds light on immune function.
Illustration of immune cell opening as if on hinge and boxing glove coming out.
Q&A
New Approach Could Boost Immunotherapy for Breast Cancer

A protein on certain immune cells is a promising target for making immunotherapy more effective against breast cancer.
a circuit board
Feature
After Years of Neglect, Cancer Biologists Return to a Forgotten Field: Metabolism

Scientists are dusting off their biochemistry textbooks in the hunt for clues to cancer.
Bees in a hive
In the Lab
Communal Behavior within Cells Makes Cancers Easier to Target

Findings about proteins called molecular chaperones are shedding new light on possible approaches to cancer treatment.
A chess match
In the Lab
Resistance Is Futile: Targeted Treatment Makes Stubborn Cancers Responsive to Immunotherapy

New research on an experimental drug provides hope for better responses to immunotherapy.
Christine Mayr, MD, PhD
Molecular Biologist Christine Mayr of Sloan Kettering Institute Honored with Prestigious NIH Director’s Pioneer Award

Molecular biologist Christine Mayr, MD, PhD, of Memorial Sloan Kettering’s (MSK) Sloan Kettering Institute (SKI) is one of 12 2016 recipients of the prestigious National Institutes of Health (NIH) Director’s Pioneer Award. Established in 2004, the annual award recognizes and supports individual scientists of exceptional creativity who propose pioneering and highly innovative approaches with the potential to produce an unusually high impact on biomedical or behavioral research.