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fluorescent cells
Small Number of ‘Highly Plastic’ Cancer Cells Drive Disease Progression and Treatment Resistance

A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer progression and its ability to evolve resistance to treatment, MSK researchers have found in a laboratory study of lung cancer.
A researcher working in an MSK lab
MSK Research Highlights, January 20, 2026

New MSK research sheds new light on how the gut protects itself by sensing gut bacteria; finds a subtype of glioma-associated macrophages that appear to play a pivotal role in progression; and demonstrates that reduced surgery is an option for some thyroid cancer patients.
Cancer cells on a screen
Making Progress Against Metastasis

While there has been remarkable progress in the number of people surviving with stage 4 cancer, MSK remains dedicated to research that will spur much needed advances.
Scientific image showing spindle-shaped and round dormant metastatic cancer cells
Dormant Cancer Cells Change Shape To Survive Immune System Attack

New MSK research reveals how dormant metastatic cancer cells protect themselves from the immune system by changing their shape.
A researcher working in an MSK lab
MSK Research Highlights, December 16, 2025

New MSK research finds a way to package protein-degrading drugs called PROTACs into nanoparticles that target blood vessels within solid tumors; identifies genomic markers that predict whether precancerous blood conditions will turn into multiple myeloma; develops a data-driven approach that could catch lymphedema earlier; and shows that nurse-led palliative care delivered by phone could serve as a scalable model.
microscope image of regulatory T cells
MSK Researchers Solve a Key Colorectal Cancer Mystery

A new MSK study finds that in colorectal cancer, not all regulatory T cells are created equal. One subtype suppresses cancer growth while another aids it. The findings could help improve immunotherapy treatment for the majority of patients with colorectal cancer, and potentially for other cancers.
Binglong Zhang at work in the lab
Top Cancer Research Advances at MSK in 2025

MSK researchers continued to make strides against cancer in 2025. Learn about some of their top discoveries.
Q&A
Dr. Omar Abdel-Wahab in his lab
Meet Omar Abdel-Wahab: A 2025 Paul Marks Prize Recipient 

A leader in developing better treatments for a range of blood cancers, Dr. Omar Abdel-Wahab is only the second person from MSK to receive the Paul Marks Prize for Cancer Research. 
Lab coat with the MSK logo hangs in a lab
MSK Research Highlights, November 20, 2025

New MSK research finds a potential therapeutic opportunity in regulatory T cells’ resilience to the loss of Foxp3; shows how cancer develops resistance to antibody-drug conjugates; develops a new system to help make gene editing safer and more reliable; and shows provider billing margin doesn’t drive cancer treatment selection.
A researcher points to cells on a screen
Memorial Sloan Kettering Cancer Center Applauds Highly Cited Researchers 2025

In 2025, MSK was again ranked among the top organizations with the greatest number of highly cited scientific researchers worldwide, according to the annual list of Highly Cited Researchers, published by the Institute for Scientific Information at Clarivate.