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A researcher working in an MSK lab
MSK Research Highlights, March 2, 2026

New MSK research finds the TCA cycle’s waste-management function may present an opportunity against cancer; shows how microplastics impair immune ‘housekeeping’ functions; reveals the way the protein TOX plays different roles in different immune cells; and identifies a new combination approach for treating advanced kidney cancer after immunotherapy.
A researcher working in an MSK lab
MSK Research Highlights, February 23, 2026

New MSK research investigates harnessing the power of ferroptosis to spread cell death; reports how an MSK artificial intelligence (AI) model could help improve patient safety; and uses AI to reveal country-specific drivers of global cancer outcomes.
A researcher working in an MSK lab
MSK Research Highlights, February 4, 2026

New MSK research illuminates new details about Thetis cells that will support efforts to harness them therapeutically; shows how the timing and strength of danger signals steer immune cell fates; and employs single-nucleus DNA sequencing to shed new light on the evolution of pancreatic cancer.
fluorescent cells
Small Number of ‘Highly Plastic’ Cancer Cells Drive Disease Progression and Treatment Resistance

A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer progression and its ability to evolve resistance to treatment, MSK researchers have found in a laboratory study of lung cancer.
A researcher working in an MSK lab
MSK Research Highlights, January 20, 2026

New MSK research sheds new light on how the gut protects itself by sensing gut bacteria; finds a subtype of glioma-associated macrophages that appear to play a pivotal role in progression; and demonstrates that reduced surgery is an option for some thyroid cancer patients.
Cancer cells on a screen
Making Progress Against Metastasis

While there has been remarkable progress in the number of people surviving with stage 4 cancer, MSK remains dedicated to research that will spur much needed advances.
Scientific image showing spindle-shaped and round dormant metastatic cancer cells
Dormant Cancer Cells Change Shape To Survive Immune System Attack

New MSK research reveals how dormant metastatic cancer cells protect themselves from the immune system by changing their shape.
A researcher working in an MSK lab
MSK Research Highlights, December 16, 2025

New MSK research finds a way to package protein-degrading drugs called PROTACs into nanoparticles that target blood vessels within solid tumors; identifies genomic markers that predict whether precancerous blood conditions will turn into multiple myeloma; develops a data-driven approach that could catch lymphedema earlier; and shows that nurse-led palliative care delivered by phone could serve as a scalable model.
microscope image of regulatory T cells
MSK Researchers Solve a Key Colorectal Cancer Mystery

A new MSK study finds that in colorectal cancer, not all regulatory T cells are created equal. One subtype suppresses cancer growth while another aids it. The findings could help improve immunotherapy treatment for the majority of patients with colorectal cancer, and potentially for other cancers.
Binglong Zhang at work in the lab
Top Cancer Research Advances at MSK in 2025

MSK researchers continued to make strides against cancer in 2025. Learn about some of their top discoveries.