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16 News Items found
In the Lab
DNA winding around histones
Research Clarifies How IDH Mutations Cause Cancer

The MSK team’s goal was to get at the underlying defects in cells that these mutations cause.
In the Lab
A cartoon depicting a cleaning crew
Cellular “Garbage Collectors” Are Key to Cancer’s Growth

A new study suggests a way to target cancer by interfering with its system of waste removal.
Feature
Omar Abdel-Wahab
What Is Epigenetics, and Why Is Everyone Talking about It?

The word “epigenetic” literally means “above the genes.” Calico cats demonstrate a type of epigenetic inheritance called X-inactivation.
In Brief
Illustration of girl standing in front of charging bull
Scientists Identify How Gene Mutation Drives a Deadly Childhood Cancer

Synovial sarcoma is an aggressive cancer primarily affecting children and young adults. A new study gets to the bottom of it.
Feature
Former MSK president Paul Marks
The Man behind the Prize: How Paul Marks Shaped Modern Cancer Research

Recent advances in epigenetic and targeted therapies owe a lot to the foresight of former MSK President Paul Marks, who believed in the importance of basic research.
In the Lab
A scientist looks at illustrations of chromosomes.
When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma

The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.
In the Lab
Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.
Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.
In the Lab
MSK scientists Charles Rudin and John Poirier
Scientists Home in on Treatment Advance for Chemotherapy-Resistant Small Cell Lung Cancer

An epigenetic mechanism may make small cell lung cancer vulnerable to a new kind of attack.
Q&A
photo of sugary foods like candy, donuts, and cupcakes
No Sugar, No Cancer? A Look at the Evidence

A lot has been written about the relationship between sugar and cancer. Most of it is wrong.
Feature
a circuit board
After Years of Neglect, Cancer Biologists Return to a Forgotten Field: Metabolism

Scientists are dusting off their biochemistry textbooks in the hunt for clues to cancer.